![](/CAS/GIF/53487-52-8.gif)
P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER synthesis
- Product Name:P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER
- CAS Number:53487-52-8
- Molecular formula:C11H12O3S
- Molecular Weight:224.28
![Tosyl chloride](/CAS/GIF/98-59-9.gif)
98-59-9
586 suppliers
$9.00/5g
![3-Butyn-2-ol](/CAS/GIF/2028-63-9.gif)
2028-63-9
207 suppliers
$10.00/1g
![P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER](/CAS/GIF/53487-52-8.gif)
53487-52-8
58 suppliers
$33.00/500mg
Yield:53487-52-8 95%
Reaction Conditions:
with potassium hydroxide
Steps:
2.a a
a 2-Tosyloxy-3-butyne To a solution of tosyl chloride (0.5 mole) and commercial 3-butyn-2-ol (0.4 mole; 40-50% aqueous solution) in ether (350 ml), potassium hydroxide (2.5 moles) is slowly added over a period of 15-30 minutes. The temperature is maintained at 0°-5° C. for the entire period and the reaction mixture is allowed to stand for 90 minutes. When the reaction is complete, the ether phase is washed and dried. Removal of the ether, in vacuo, yields crude 2-tosyloxy-3-butyne. (m.p. 49°-51° C.; yield 95%).
References:
US5436273,1995,A
![Tosyl chloride](/CAS/GIF/98-59-9.gif)
98-59-9
586 suppliers
$9.00/5g
![P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER](/CAS/GIF/53487-52-8.gif)
53487-52-8
58 suppliers
$33.00/500mg
![Propargyl alcohol](/CAS/GIF/107-19-7.gif)
107-19-7
5 suppliers
$12.00/25g
![3-Butyn-2-ol](/CAS/GIF/2028-63-9.gif)
2028-63-9
207 suppliers
$10.00/1g
![P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER](/CAS/GIF/53487-52-8.gif)
53487-52-8
58 suppliers
$33.00/500mg
![3-Butyn-2-ol](/CAS/GIF/2028-63-9.gif)
2028-63-9
207 suppliers
$10.00/1g
![P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER](/CAS/GIF/53487-52-8.gif)
53487-52-8
58 suppliers
$33.00/500mg