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(PHENOXYACETYL)AMINO]ACETIC ACID synthesis

1synthesis methods
-

Yield:14231-45-9 57%

Reaction Conditions:

sodium hydroxide in water;

Steps:

59.A A.

A. Phenoxyacetyl glycine Glycine (20 mmol) was reacted with distilled phenoxyacetyl chloride (22 mmol) in the presence of NaOH (40 mmol) in a mixture of water and ether as described in Example 5 Part A. The crude product was recrystallized from EtOAc (15 ml) to give title acid (2.38 gm, 57%).

References:

US4663336,1987,A US4734424,1988,A

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