PHENYLMAGNESIUM CHLORIDE synthesis
- Product Name:PHENYLMAGNESIUM CHLORIDE
- CAS Number:100-59-4
- Molecular formula:C6H5ClMg
- Molecular Weight:136.86
108-90-7
643 suppliers
$10.00/25G
100-59-4
256 suppliers
$38.00/0.25mole
Yield:100-59-4 95%
Reaction Conditions:
with magnesium in tetrahydrofuran at 45 - 60; for 5 h;
Steps:
1.1 Step 1 Preparation of Phenylmagnesium Chloride Grignard Reagent
In a 1 L reaction flask, 283.32 g of tetrahydrofuran and 22.18 g (0.924 mol) of magnesium turnings were added.94.44 g (0.84 mol) of chlorobenzene and 94.44 g of tetrahydrofuran were added to the dropping funnel.A small amount of chlorobenzene is added into the reaction flask, and stirring is started. After the reaction is initiated, the temperature of the system is raised to 45 to 50 ° C.Turn on the remaining chlorobenzene solution and keep the temperature of the reaction system between 45 and 50 °C. After the addition is completed, the reaction is kept for 5 hours.Sampling, testing the reaction of the raw materials, the reaction bottle is cooled to 20 ~ 25 ° C, under nitrogen protection, stored for use. The yield was 95%.
References:
Lianhua Science And Technology (Shanghai) Co., Ltd.;Lianhua Technology Co., Ltd.;Liaoning Tian Yu Chemical Co., Ltd.;Hubei Jun Tai Pharmaceutical And Chemical Co., Ltd.;Fan Xiaobin;Guo Zhanghong;Jiang Peng CN105198682, 2018, B Location in patent:Paragraph 0073; 0074; 0075
7439-95-4
8 suppliers
$11.60/0.9g
108-90-7
643 suppliers
$10.00/25G
100-59-4
256 suppliers
$38.00/0.25mole
591-50-4
472 suppliers
$10.00/1g
100-59-4
256 suppliers
$38.00/0.25mole