ChemicalBook CAS DataBase List Potassium cyclohexyltrifluoroborate

Potassium cyclohexyltrifluoroborate synthesis

8synthesis methods

Product Name:Potassium cyclohexyltrifluoroborate
CAS Number:446065-11-8
Molecular formula:C6H11BF3.K
Molecular Weight:190.056

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Yield: 79%

Reaction Conditions:

in methanol;water for 2 h;Inert atmosphere;

Steps:

General synthesis of alkyl trifluoroborates [1].
General procedure: To the solution of alkyl boronic acidor pinacol ester (10 mmol) in methanol (20 mL) was added saturated aqueous KHF2(15 mL, 3.91 g, 50 mmol, 5.0 equiv). The resulting suspension was stirred for 2 h andthen concentrated to dryness. The residue, a white solid, was extracted with hotacetone, and the combined filtered extracts were concentrated to approximately 5 mL.Ether (or CH2Cl2) was added and the resultant precipitate was collected and dried toafford the potassium trifluoroborate as a white solid.

References:

Pan, Yue;Jia, Kunfang;Chen, Yali;Chen, Yiyun [Beilstein Journal of Organic Chemistry,2018,vol. 14,p. 1215 - 1221] Location in patent:supporting information