(prop-2-yn-1-yloxy)cyclopentane synthesis
1synthesis methods
- Product Name:(prop-2-yn-1-yloxy)cyclopentane
- CAS Number:118464-10-1
- Molecular formula:C8H12O
- Molecular Weight:124.18
Yield:118464-10-1 90%
Reaction Conditions:
Stage #1: Cyclopentanolwith sodium hydride in tetrahydrofuran;mineral oil; for 0.5 h;Inert atmosphere;
Stage #2: propargyl bromide in tetrahydrofuran;toluene;mineral oil at 20;Inert atmosphere;Reflux;
References:
Goren, Kerem;Kehat, Tzofit;Portnoy, Moshe [Advanced Synthesis and Catalysis,2009,vol. 351,# 1-2,p. 59 - 65] Location in patent:supporting information; experimental part