(R)-2-CHLOROSUCCINIC ACID synthesis
- Product Name:(R)-2-CHLOROSUCCINIC ACID
- CAS Number:3972-40-5
- Molecular formula:C4H5ClO4
- Molecular Weight:152.53
1783-96-6
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Yield: 95%
Reaction Conditions:
Stage #1:(2R)-aspartic acid with hydrogenchloride;potassium bromide;sodium nitrite in water at 0 - 5; for 4 h;
Stage #2: with urea for 0.166667 h;
References:
Wu, Yan;Liu, Min-Jie;Huang, Hai-Qing;Huang, Guan-Xin;Xiong, Fang-Jun;Chen, Fen-Er [European Journal of Organic Chemistry,2017,vol. 2017,# 25,p. 3681 - 3688]
56-84-8
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97-67-6
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617-45-8
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