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ChemicalBook CAS DataBase List (RS)-1-[4-(TRIFLUOROMETHYL)PHENYL]PROPYLAMINE

(RS)-1-[4-(TRIFLUOROMETHYL)PHENYL]PROPYLAMINE synthesis

2synthesis methods
-

Yield:> 99 % ee

Reaction Conditions:

with pyridoxal 5'-phosphate;transaminase ATA-025;isopropylamine in aq. phosphate buffer;dimethyl sulfoxide at 30; pH=7.5; for 24 h;Enzymatic reaction;stereoselective reaction;Reagent/catalyst;

References:

Martínez-Montero, Lía;Gotor, Vicente;Gotor-Fernández, Vicente;Lavandera, Iván [Green Chemistry,2017,vol. 19,# 2,p. 474 - 480] Location in patent:supporting information