ChemicalBook CAS DataBase List (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol synthesis

12synthesis methods

Product Name:(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol
CAS Number:22323-82-6
Molecular formula:C6H12O3
Molecular Weight:132.16

16495-03-7 Synthesis

(S)-4-BENZYLOXYMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE

16495-03-7
84 suppliers
$55.00/500mg

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

22323-82-6
302 suppliers
$8.00/1g

Yield:22323-82-6 91%

Reaction Conditions:

palladium-carbon in ethyl acetate

Steps:

5 EXAMPLE 5
10% Palladium-carbon (2.7 g) was added to thus obtained (S)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane (16.228 g, 73.02 mmol) in ethyl acetate(270 ml) and the mixture was stirred for 3 hours at 25° C. under an atmosphere of hydrogen. After the reaction was over, palladium-carbon was filtered off and the solvent was condensed in vacuo. The crude product was distilled to give 8.78 g of (S)-2,2-dimethyl-1,3-dioxolane-4-methanol (yield 91%, b.p. 70° C. at 6 mmHg, optical purity 97.2% e.e., specific rotation [α]_D²⁰ +10.76°(c=1,MeOH))).

References:

Daiso Co., Ltd. US6124479, 2000, A

FullText

1707-77-3 Synthesis

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol

1707-77-3
357 suppliers
$5.00/5g

22323-82-6
302 suppliers
$8.00/1g

References

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

15186-48-8
323 suppliers
$8.00/5g

22323-82-6
302 suppliers
$8.00/1g

References

1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-acetate, (4R)-

57415-98-2
0 suppliers
inquiry

22323-82-6
302 suppliers
$8.00/1g

References

1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-benzoate, (4R)-

51432-60-1
0 suppliers
inquiry

22323-82-6
302 suppliers
$8.00/1g

References

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