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ChemicalBook CAS DataBase List (S)-tert-butyl (1-methylpiperidin-3-yl)carbamate

(S)-tert-butyl (1-methylpiperidin-3-yl)carbamate synthesis

6synthesis methods
216854-23-8 Synthesis
(S)-3-N-Boc-aminopiperidine

216854-23-8
314 suppliers
$6.00/250mg

(S)-tert-butyl (1-methylpiperidin-3-yl)carbamate

902152-77-6
5 suppliers
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Yield:902152-77-6 90%

Reaction Conditions:

with formic acid in 2-methyltetrahydrofuran;water at 80; for 0.75 h;

References:

Humphreys, Philip G.;Bamborough, Paul;Chung, Chun-Wa;Craggs, Peter D.;Gordon, Laurie;Grandi, Paola;Hayhow, Thomas G.;Hussain, Jameed;Jones, Katherine L.;Lindon, Matthew;Michon, Anne-Marie;Renaux, Jessica F.;Suckling, Colin J.;Tough, David F.;Prinjha, Rab K. [Journal of Medicinal Chemistry,2017,vol. 60,# 2,p. 695 - 709] Location in patent:supporting information