ChemicalBook CAS DataBase List SIB-1893

SIB-1893 synthesis

11synthesis methods

Product Name:SIB-1893
CAS Number:7370-21-0
Molecular formula:C14H13N
Molecular Weight:195.26

108-48-5 Synthesis

108-48-5
461 suppliers
$9.90/190μL

100-52-7 Synthesis

100-52-7
941 suppliers
$20.37/250g

7370-21-0
11 suppliers
$140.00/10mg

Yield:7370-21-0 62%

Reaction Conditions:

with tert-butylammonium hexafluorophosphate(V);calcium(II) trifluoromethanesulfonate in neat (no solvent) at 130; for 8 h;Green chemistry;

Steps:

B. General experimental procedure for the synthesis of stryryl azaarenes:

General procedure: A mixture of 2-methyl quinoline (1 mmol), aryl aldehyde (1 mmol), Ca (OTf)2 (5 mol%) andBu4NPF6 (2 mol%) were heated at 130 oC under neat condition for 4-5 h. After completion of the reaction (monitored by TLC), reaction mixture was brought to roomtemperature, diluted with dichloromethane, absorbed on silica gel and purified by column chromatography using petroleum ether/ethyl acetate to give the desired product.

References:

Yaragorla, Srinivasarao;Singh, Garima;Dada, Ravikrishna [Tetrahedron Letters,2015,vol. 56,# 43,p. 5924 - 5929] Location in patent:supporting information

96206-92-7 Synthesis