Stearoylbenzoylmethane synthesis
- Product Name:Stearoylbenzoylmethane
- CAS Number:58446-52-9
- Molecular formula:C26H42O2
- Molecular Weight:386.61
112-61-8
392 suppliers
$8.00/25g
14593-46-5
272 suppliers
$15.00/5g
98-86-2
738 suppliers
$9.00/5g
58446-52-9
220 suppliers
$22.00/250mg
Yield:58446-52-9 74%
Reaction Conditions:
with sulfuric acid in water;sodium hydrogencarbonate
Steps:
6 Preparation of Benzoylstearoylmethane (SBM)
Example 6 Preparation of Benzoylstearoylmethane (SBM) Xylenes (dry, 180 mL), sodium tert-pentoxide (17.9 g; 0.163 mol), and methyl stearate (41.5 g; 0.139 mol) were placed into a four-necked, round bottom, half-liter flask equipped with a stirrer, a thermometer, and a reflux condenser with a distillation valve. The mixture was heated to 120° C. and kept at that temperature under a blanket of nitrogen. Acetophenone (15.0 g; 0.125 mol) was added slowly over a period of 30 minutes by means of a syringe pump. After 42 minutes, the distillation valve was opened and the distillate was removed as the reaction proceeded. After 1:05 hours from the beginning of the addition of the ketone, the mixture was cooled down to room temperature. Aqueous sulfuric acid (16%) was added with stirring until the pH of the aqueous layer was acidic. The organic layer was washed in a separation funnel with aqueous sodium bicarbonate and then with water. The solvents were evaporated on a Rotovap, and the solid residue was crystallized from methanol, affording SBM (35.7 g, 74% yield) having a purity of 98% (GC).
References:
Crompton Corporation US6410795, 2002, B1
112-61-8
392 suppliers
$8.00/25g
98-86-2
738 suppliers
$9.00/5g
58446-52-9
220 suppliers
$22.00/250mg
91-01-0
499 suppliers
$6.00/10g
112-61-8
392 suppliers
$8.00/25g
98-86-2
738 suppliers
$9.00/5g
58446-52-9
220 suppliers
$22.00/250mg
111-61-5
237 suppliers
$8.00/5g
98-86-2
738 suppliers
$9.00/5g
58446-52-9
220 suppliers
$22.00/250mg