ChemicalBook CAS DataBase List tert-Butyl N-cyclohexylcarbaMate

tert-Butyl N-cyclohexylcarbaMate synthesis

13synthesis methods

Product Name:tert-Butyl N-cyclohexylcarbaMate
CAS Number:3712-40-1
Molecular formula:C11H21NO2
Molecular Weight:199.29

108-91-8 Synthesis

108-91-8
599 suppliers
$10.00/5mL

49761-82-2 Synthesis

49761-82-2
143 suppliers
$5.00/1g

3712-40-1
13 suppliers
$265.00/2.5g

Yield:3712-40-1 92%

Reaction Conditions:

with Imidazole hydrochloride in water at 20; for 0.166667 h;

Steps:

Synthesis of 1-morpholino-2-phenyl ethanone

General procedure: In a round bottomed flask 0.01 mol (1.36 g) phenyl acetic acid and 0.012 mol (1.94 g) of CDI were added. The reaction mixture was mixed and grinded with a spatula. CO₂ gas starts releasing with increase in temperature and solid reaction mixture was turned to pale yellow liquid within 5 min. 0.001 mol (0.1 g) Imidazole. hydrochloride, 0.01 mol (0.87 g) of morpholine, and 1 mL of water were added to it. The reaction mixture was kept at room temperature for another 10 min. Dilute hydrochloride solution was added to it and the aqueous layer was washed with ethyl acetate. The organic layer was dried over anhydrous Na₂SO₄ and concentrated to give pure product.

References:

Verma, Sanjeev K.;Ghorpade, Ramarao;Pratap, Ajay;Kaushik [Tetrahedron Letters,2012,vol. 53,# 19,p. 2373 - 2376] Location in patent:experimental part

24424-99-5 Synthesis