![](/CAS/GIF/123-93-3.gif)
Thiodiglycolic acid synthesis
- Product Name:Thiodiglycolic acid
- CAS Number:123-93-3
- Molecular formula:C4H6O4S
- Molecular Weight:150.15
![L-Methionine](/CAS/GIF/63-68-3.gif)
63-68-3
885 suppliers
$5.00/25g
![Chloroacetic acid](/CAS/GIF/79-11-8.gif)
79-11-8
10 suppliers
$24.00/25g
![(METHYLTHIO)ACETIC ACID](/CAS/GIF/2444-37-3.gif)
2444-37-3
78 suppliers
$7.00/250mg
![Thiodiglycolic acid](/CAS/GIF/123-93-3.gif)
123-93-3
278 suppliers
$8.00/25g
![L-Homoserine lactone hydrochloride](/CAS/GIF/2185-03-7.gif)
2185-03-7
250 suppliers
$5.00/100mg
Yield:-
Reaction Conditions:
in water at 80; for 8 h;Overall yield = 162.1 g;
Steps:
5.1 (1) Preparation of compounds IV, V, VI:
To a 1 L four-necked flask, 90 g (0.6 mol) of L-methionine, 79.4 g (0.84 mol) of chloroacetic acid, and 500 ml of water were added, and the mixture was stirred uniformly, and slowly heated to 80 ° C to carry out a reaction for 8 hours; After the reaction is over, recovering solvent water under reduced pressure and reduced pressure, a total of 162.1 g of a mixture of L-homoserine lactone hydrochloride, (methylthio)acetic acid and thiodiacetic acid was obtained, and the next step reaction was carried out without isolation;
References:
Shandong Nong Pharmaceutical Xue Institute;Xie Yinping;Chai Hongwei;Dong Wenkai;Han Jintao;Cong Yunbo;Wang Xiuli;Zhang Zuoshan;Li Xukun CN108774160, 2018, A Location in patent:Paragraph 0076; 0078
![Chloroacetic acid](/CAS/GIF/79-11-8.gif)
79-11-8
10 suppliers
$24.00/25g
![Thiodiglycolic acid](/CAS/GIF/123-93-3.gif)
123-93-3
278 suppliers
$8.00/25g
![D-Methionine](/CAS/GIF/348-67-4.gif)
348-67-4
382 suppliers
$5.00/1g
![Chloroacetic acid](/CAS/GIF/79-11-8.gif)
79-11-8
10 suppliers
$24.00/25g
![(METHYLTHIO)ACETIC ACID](/CAS/GIF/2444-37-3.gif)
2444-37-3
78 suppliers
$7.00/250mg
![Thiodiglycolic acid](/CAS/GIF/123-93-3.gif)
123-93-3
278 suppliers
$8.00/25g
![(R)-(+)-alpha-Amino-gamma-butyrolactone hydrochloride](/CAS/GIF/104347-13-9.gif)
104347-13-9
168 suppliers
$5.00/100mg
![Chloroacetic acid](/CAS/GIF/79-11-8.gif)
79-11-8
10 suppliers
$24.00/25g
![DL-Methionine](/CAS/GIF/59-51-8.gif)
59-51-8
799 suppliers
$5.00/100mg
![(METHYLTHIO)ACETIC ACID](/CAS/GIF/2444-37-3.gif)
2444-37-3
78 suppliers
$7.00/250mg
![Thiodiglycolic acid](/CAS/GIF/123-93-3.gif)
123-93-3
278 suppliers
$8.00/25g
![DL-Homoserine Lactone hydrochloride](/CAS/20180703/GIF/42417-39-0.gif)
42417-39-0
47 suppliers
$104.00/10g
![Thioglycolic acid](/CAS/GIF/68-11-1.gif)
68-11-1
404 suppliers
$12.00/25g
![Thiodiglycolic acid](/CAS/GIF/123-93-3.gif)
123-93-3
278 suppliers
$8.00/25g