ChemicalBook CAS DataBase List TRIETHYL 3-PHOSPHONOPROPIONATE

TRIETHYL 3-PHOSPHONOPROPIONATE synthesis

10synthesis methods

Product Name:TRIETHYL 3-PHOSPHONOPROPIONATE
CAS Number:3699-67-0
Molecular formula:C9H19O5P
Molecular Weight:238.22

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Yield:3699-67-0 93%

Reaction Conditions:

with triethyl phosphite

Steps:

1 EXAMPLE 1

EXAMPLE 1 Triethyl Phosphonopropionate: Ethyl bromopropionate (92 g 0.5 mole) and triethyl phosphite (83 g, 0.5 mole) were stirred and heated to about 200° C. under a air cooled reflux condenser. The ethyl bromide that was evolved was collected with the aid of a cooling trap. After 1 hour of heating the pot temperature went up to 230° C. At this point the evolution of ethyl bromide ceased. The yellow oil was cooled to room temperature (RT) and then distilled under vacuum. There was obtained 112 g of phosphonate (93%) boiling at 105° /20 mm Hg as a colorless oil.

References:

US5162566,1992,A