ChemicalBook CAS DataBase List UNC0638

UNC0638 synthesis

8synthesis methods

Product Name:UNC0638
CAS Number:1255580-76-7
Molecular formula:C30H47N5O2
Molecular Weight:509.73

4421-08-3 Synthesis

4421-08-3
140 suppliers
$6.00/5g

1255580-76-7
96 suppliers
$38.00/1mg

Yield:-

Steps:

Multi-step reaction with 9 steps
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2: nitric acid; acetic anhydride / 0 - 20 °C
3: water; iron; ammonium chloride / isopropyl alcohol / Reflux
4: N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 0 - 20 °C
5: dihydrogen peroxide; sodium hydroxide / ethanol; water / 2 h / Reflux
6: N,N-diethylaniline; trichlorophosphate / 4 h / Reflux
7: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 0.25 h / 160 °C / Microwave irradiation
8: palladium 10% on activated carbon; cyclohexa-1,4-diene / ethanol / 2 h / Reflux
9: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere

References:

Liu, Feng;Barsyte-Lovejoy, Dalia;Allali-Hassani, Abdellah;He, Yunlong;Herold, J. Martin;Chen, Xin;Yates, Christopher M.;Frye, Stephen V.;Brown, Peter J.;Huang, Jing;Vedadi, Masoud;Arrowsmith, Cheryl H.;Jin, Jian [Journal of Medicinal Chemistry,2011,vol. 54,# 17,p. 6139 - 6150]