![](/CAS/20150408/GIF/1481677-78-4.gif)
UNC-0642 synthesis
- Product Name:UNC-0642
- CAS Number:1481677-78-4
- Molecular formula:C29H44F2N6O2
- Molecular Weight:546.7
![Methyl vanillate](/CAS/GIF/3943-74-6.gif)
3943-74-6
338 suppliers
$5.00/100mg
![UNC-0642](/CAS/20150408/GIF/1481677-78-4.gif)
1481677-78-4
73 suppliers
$36.00/1mg
Yield:-
Steps:
Multi-step reaction with 8 steps
1.1: potassium carbonate / acetonitrile / Reflux
2.1: nitric acid; acetic anhydride / 0 - 20 °C
3.1: potassium carbonate; sodium iodide; tetra-(n-butyl)ammonium iodide / acetonitrile / Reflux
4.1: iron; ammonium acetate / ethyl acetate; water / Reflux
5.1: acetic acid / water / 20 °C
5.2: Reflux
6.1: trichlorophosphate / N,N-dimethyl-aniline / Reflux
7.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C
8.1: trifluoroacetic acid / isopropyl alcohol / 0.25 h / 160 °C / Microwave irradiation; Sealed tube
References:
Liu, Feng;Barsyte-Lovejoy, Dalia;Li, Fengling;Xiong, Yan;Korboukh, Victoria;Huang, Xi-Ping;Allali-Hassani, Abdellah;Janzen, William P.;Roth, Bryan L.;Frye, Stephen V.;Arrowsmith, Cheryl H.;Brown, Peter J.;Vedadi, Masoud;Jin, Jian [Journal of Medicinal Chemistry,2013,vol. 56,# 21,p. 8931 - 8942]
![Methyl 2-aMino-5-Methoxy-4-(3-(pyrrolidin-1-yl)propoxy)benzoate](/CAS/20150408/GIF/1320288-24-1.gif)
1320288-24-1
5 suppliers
inquiry
![UNC-0642](/CAS/20150408/GIF/1481677-78-4.gif)
1481677-78-4
73 suppliers
$36.00/1mg
![2,4-Dichloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline](/CAS/GIF/1320288-30-9.gif)
1320288-30-9
18 suppliers
inquiry
![UNC-0642](/CAS/20150408/GIF/1481677-78-4.gif)
1481677-78-4
73 suppliers
$36.00/1mg
![Methyl 4-(3-chloropropoxy)-5-Methoxy-2-nitrobenzoate](/CAS/20150408/GIF/214470-57-2.gif)
214470-57-2
43 suppliers
inquiry
![UNC-0642](/CAS/20150408/GIF/1481677-78-4.gif)
1481677-78-4
73 suppliers
$36.00/1mg
![Methyl 4-(3-chloropropoxy)-3-Methoxybenzoate](/CAS/20150408/GIF/111627-40-8.gif)
111627-40-8
19 suppliers
inquiry
![UNC-0642](/CAS/20150408/GIF/1481677-78-4.gif)
1481677-78-4
73 suppliers
$36.00/1mg