Thiamine Hcl
- CAS No.
- 67-03-8
- Chemical Name:
- Thiamine Hcl
- Synonyms
- THIAMINE;THIAMINE HCL;thd;VITAMIN B1 HCL;Vitamin B1 Thiamine;THIAMIN HYDROCHLORIDE;VIT B1;VB1 HCL;200-641-8;ThiaMine hydro
- CBNumber:
- CB00131314
- Molecular Formula:
- C12H17N4OS.ClH.Cl
- Molecular Weight:
- 337.27
- MDL Number:
- MFCD00012780
- MOL File:
- 67-03-8.mol
- MSDS File:
- SDS
| Melting point | 250 °C (dec.)(lit.) |
|---|---|
| Density | 1.3766 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| FEMA | 3322 | THIAMINE HYDROCHLORIDE |
| Flash point | 9°C |
| storage temp. | room temp |
| solubility | H2O: 0.1 g/mL at 20 °C, clear, colorless |
| pka | pKa 4.8 (Uncertain);9.0 (Uncertain) |
| form | Crystalline Powder |
| color | White to almost white |
| PH | 2.7-3.3 |
| Odor | sour mild bitter |
| Odor Type | bland |
| Water Solubility | 1 g/mL |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 14,9295 |
| JECFA Number | 1030 |
| BRN | 3851771 |
| BCS Class | 3 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents. |
| LogP | -3.93 |
| FDA 21 CFR | 184.1875; 582.5875; 136.115; 137.165; 137.185; 310.545 |
| Substances Added to Food (formerly EAFUS) | THIAMINE HYDROCHLORIDE |
| SCOGS (Select Committee on GRAS Substances) | Thiamine hydrochloride |
| CAS DataBase Reference | 67-03-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | thiamine |
| FDA UNII | M572600E5P |
| NCI Drug Dictionary | thiamine |
| EPA Substance Registry System | Thiamine hydrochloride (67-03-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xi,T,F | |||||||||
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36-45-36/37-16-7 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | XI7350000 | |||||||||
| F | 3-8-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29362200 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 89.2 i.v.; 8224 orally (Winter) | |||||||||
| NFPA 704 |
|
Thiamine Hcl price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W332208 | Thiamine hydrochloride ≥98%, FCC, FG | 67-03-8 | sample-k | $54.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | W332208 | Thiamine hydrochloride ≥98%, FCC, FG | 67-03-8 | 1kg | $169 | 2024-03-01 | Buy |
| Sigma-Aldrich | W332208 | Thiamine hydrochloride ≥98%, FCC, FG | 67-03-8 | 5kg | $789 | 2024-03-01 | Buy |
| Sigma-Aldrich | T4625 | Thiamine hydrochloride reagent grade, ≥99% (HPLC) | 67-03-8 | 5G | $20.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | T4625 | Thiamine hydrochloride reagent grade, ≥99% (HPLC) | 67-03-8 | 10g | $38.7 | 2024-03-01 | Buy |
Thiamine Hcl Chemical Properties,Uses,Production
Description
Thiamine Hcl is the hydrochloride salt form of thiamine (vitamin B1), a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Vitamin B1 helps prevent various health problems including heart damage. Thiamine Hcl is a white or almost white, crystalline powder or colorless crystals. It has an odor slightly reminiscent of thiazole and a bitter taste. Very soluble in water (1g dissolved in 1mL of water at 20℃), slightly soluble in ethanol, and insoluble in ether, benzene, chloroform, and acetone. The oxidation-reduction reaction can cause it to lose activity. When exposed to air, the vitamin rapidly absorbs about 4% of water.
Uses
Thiamine Hcl is used to prevent and treat thiamine deficiency states, which may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used for the treatment of Wernicke-Korsakoff syndrome, beriberi and thiamine deficiency related to chronic alcoholism. Thiamine hydrochloride is used as a food additive to add brothy/meaty flavor to gravies or soups. It is used also as a food supplement and flavoring ingredient with a bitter taste.
Biochem/physiol Actions
Thiamine Hcl is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiamine Hcl is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is a coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism.
Thiamine Hcl Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 19368 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales01@airuikechemical.com | China | 994 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1142 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 341 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 2999 | 58 |
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View Lastest Price from Thiamine Hcl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-24 | Vitamin B1 Thiamine HCl
67-03-8
|
US $85.00-35.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-04-28 | Vitamin B1 Powder Thiamine HCL
67-03-8
|
US $60.00 / KG | 5KG | 99 | 1000 | Hebei Yime New Material Technology Co., Ltd. | |
 |
2023-11-16 | THIAMINE HCL
67-03-8
|
US $0.00-0.00 / kg | 1kg | 99% | 500000kg | Hebei Kingfiner Technology Development Co.Ltd |
-
- Vitamin B1 Thiamine HCl
67-03-8
- US $85.00-35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Vitamin B1 Powder Thiamine HCL
67-03-8
- US $60.00 / KG
- 99
- Hebei Yime New Material Technology Co., Ltd.
-
- THIAMINE HCL
67-03-8
- US $0.00-0.00 / kg
- 99%
- Hebei Kingfiner Technology Development Co.Ltd