GANGLIOSIDE GD1A DISODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Ganglioside G
D1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside G
D1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside G
D1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside G
D1a mixture contains ganglioside G
D1a molecular species with C18:1 and C20:1 sphingoid backbones.
Chemische Eigenschaften
White powder
Verwenden
Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.
Allgemeine Beschreibung
Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.
GANGLIOSIDE GD1A DISODIUM SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
