ガングリオシドGD1A, ウシ脳由来 化学特性,用途語,生産方法
外観
白色～ほとんど白色, 粉末
溶解性
水に溶ける。
用途
免疫研究用。
説明
Ganglioside G
D1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside G
D1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside G
D1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside G
D1a mixture contains ganglioside G
D1a molecular species with C18:1 and C20:1 sphingoid backbones.
化学的特性
White powder
使用
Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.
一般的な説明
Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.
ガングリオシドGD1A, ウシ脳由来 上流と下流の製品情報
原材料
準備製品