GINSENOSIDE F2
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- CAS-Nr.
- 62025-49-4
- Englisch Name:
- GINSENOSIDE F2
- Synonyma:
- GINSENOSIDE F2;20(S)-Ginsenoside-F2;Ginsenoside F2, >=98%;-D-glucopyranosidederiv.;20(S)-Ginsenoside F2 ,98%;Ginsenoside F2, 98%, from Panax ginseng C. A. Mey.;(20S)-3β,20-Bis(β-D-glucopyranosyloxy)-5α-dammar-24-ene-12β-ol;12β-Hydroxy-5α-dammar-24-ene-3β,20-diylbis(β-D-glucopyranoside);b-D-Glucopyranoside, (3b,12b)-12-hydroxydammar-24-ene-3,20-d...;β-D-Glucopyranoside, (3β,12β)-12-hydroxydammar-24-ene-3,20-diyl bis-
- CBNumber:
- CB5316911
- Summenformel:
- C42H72O13
- Molgewicht:
- 785.01
- MOL-Datei:
- 62025-49-4.mol
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GINSENOSIDE F2 Eigenschaften
- Schmelzpunkt:
- 195-200°C
- Siedepunkt:
- 871.5±65.0 °C(Predicted)
- Dichte
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 12.91±0.70(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilität:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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GINSENOSIDE F2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ginsenoside F
2 is a ginsenoside that has been found in
P. ginseng and has diverse biological activities. It increases the proliferation of human hair dermal papilla cells (HHDPCs) and HaCaT human keratinocytes when used at concentrations of 0.01, 0.1, and 1 μM. Ginsenoside F
2 (0.5 and 2.5 mg/kg) induces hair growth and increases hair density following depilation in mice. It is cytotoxic to U373MG glioblastoma cells
in vitro (IC
50 = 50 μg/ml) and reduces tumor growth in a U373MG mouse xenograft model when administered at a dose of 35 mg/kg every other day. Ginsenoside F
2 (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in mice. It is a human intestinal bacterial metabolite of ginsenoside Rb
1 via the intermediate ginsenoside Rd .
Verwenden
Ginsenoside F2 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to regulate element-binding protein cleavage activating protein and transforming growth factor-β pathways. This control over apoptosis can lead to a control over hair growth and hair loss in mammals.
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions
3 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.
GINSENOSIDE F2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
GINSENOSIDE F2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 185)Lieferanten
62025-49-4()Verwandte Suche:
- (20S)-3β-(β-D-Glucopyranosyloxy)-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol
- (20S)-3β,20-Bis(β-D-glucopyranosyloxy)-5α-dammar-24-ene-12β-ol
- 12β-Hydroxy-5α-dammar-24-ene-3β,20-diylbis(β-D-glucopyranoside)
- 20(S)-Ginsenoside-F2
- 20(S)-Ginsenoside F2 ,98%
- -D-glucopyranosidederiv.
- GINSENOSIDE F2
- Ginsenoside F2, >=98%
- Ginsenoside F2, 98%, from Panax ginseng C. A. Mey.
- b-D-Glucopyranoside, (3b,12b)-12-hydroxydammar-24-ene-3,20-diyl bis-
- β-D-Glucopyranoside, (3β,12β)-12-hydroxydammar-24-ene-3,20-diyl bis-
- (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
- b-D-Glucopyranoside, (3b,12b)-12-hydroxydammar-24-ene-3,20-d...
- 62025-49-4
- Ginseng series
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
