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N-Methyl-1H-Indole-5-EthaneSulphonamide

CAS No.
98623-50-8
Chemical Name:
N-Methyl-1H-Indole-5-EthaneSulphonamide
Synonyms
2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide;ratriptanImpurity5;N-Methyl-1H-Indole-5-EthaneSulphomide;N-Methyl-1H-indole-5-ethanesulfonamide;N-Methyl-1H-Indole-5-EthaneSulphonamide;1H-Indole-5-ethanesulfonamide, N-methyl-;2-(1H-indol-5-yl)-N-MethylethanesulfonaMide;N-Methyl-1H-indole-5-ethanesulfonamide, >=98%;2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide;N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide)
CBNumber:
CB01023956
Molecular Formula:
C11H14N2O2S
Molecular Weight:
238.31
MDL Number:
MOL File:
98623-50-8.mol
MSDS File:
SDS
Last updated:2023-10-16 09:41:38

N-Methyl-1H-Indole-5-EthaneSulphonamide Properties

Melting point 124-125°C
Boiling point 458.4±47.0 °C(Predicted)
Density 1.316±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 11.52±0.40(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P305+P351+P338

N-Methyl-1H-Indole-5-EthaneSulphonamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M313525 N-Methyl-1H-indole-5-ethanesulfonamide 98623-50-8 500mg $180 2021-12-16 Buy
TRC M313525 N-Methyl-1H-indole-5-ethanesulfonamide 98623-50-8 2.5g $675 2021-12-16 Buy
American Custom Chemicals Corporation CHM0294434 N-METHYL-1H-INDOLE-5-ETHANE SULFONAMIDE 98.00% 98623-50-8 25G $2106.72 2021-12-16 Buy
aablocks AA005TYY N-Methyl-1h-indole-5-ethanesulfonamide 97% 98623-50-8 100mg $95 2021-12-16 Buy
AHH MT-57055 N-Methyl-1H-indole-5-ethanesulfonamide 98% 98623-50-8 25g $770 2021-12-16 Buy
Product number Packaging Price Buy
M313525 500mg $180 Buy
M313525 2.5g $675 Buy
CHM0294434 25G $2106.72 Buy
AA005TYY 100mg $95 Buy
MT-57055 25g $770 Buy

N-Methyl-1H-Indole-5-EthaneSulphonamide Chemical Properties,Uses,Production

Uses

N-Methyl-1H-indole-5-ethanesulfonamide is used as a reagent in the synthesis of Naratriptan Hydrochloride (N378730); a triptan drug used for the treatment of migraine headaches.

General Description

N-Methyl-1H-Indole-5-EthaneSulphonamide, also known as 2-(1H-Indol-5-yl)-N-methylethanesulfonamide, is a white solid.

Synthesis

At 40-45 ℃ (hydrogen pressure: 3-4 kg/cm2), 2-(3-Phenylsulf-anyl-1H-indol-5-yl)-ethanesulfonic acidmethylamide (14) (5 g, 0.014 mol) was hydrogenated in ethanol: water (7:3) (40 ml) in an autoclave for 10 h. After that, the reaction mass was cooled to room temperature, followed by removing the catalyst through filtering. The filtrate was distilled out to get N-Methyl-1H-Indole-5-EthaneSulphonamide. N-Methyl-1H-Indole-5-EthaneSulphonamide

1204192-94-8
98623-50-8
Synthesis of N-Methyl-1H-Indole-5-EthaneSulphonamide from 1H-Indole-5-ethanesulfonamide, N-methyl-3-(phenylthio)-
Global( 67)Suppliers
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Shanghai Boc Chemical Co., Ltd.
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View Lastest Price from N-Methyl-1H-Indole-5-EthaneSulphonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Methyl-1H-indole-5-ethanesulphonaMide pictures 2022-09-12 N-Methyl-1H-indole-5-ethanesulphonaMide
98623-50-8
US $0.00-0.00 / G 1G 98%min 100kg/month Shanghai Rlavie Technology Co ltd
N-Methyl-1H-Indole-5-EthaneSulphonamide pictures 2020-01-10 N-Methyl-1H-Indole-5-EthaneSulphonamide
98623-50-8
US $1.00 / g 1g 97% 100kg Career Henan Chemical Co
N-Methyl-1H-Indole-5-EthaneSulphonamide N-Methyl-1H-indole-5-ethanesulfonamide 2-(1H-indol-5-yl)-N-MethylethanesulfonaMide N-Methyl-1H-indole-5-ethanesulfonamide, >=98% N-Methyl-1H-Indole-5-EthaneSulphomide 1H-Indole-5-ethanesulfonamide, N-methyl- 2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide 2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide ratriptanImpurity5 N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide) 98623-50-8