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ChemicalBook >> CAS DataBase List >>4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Structure
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID structure
CAS No.
39793-31-2
Chemical Name:
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
Synonyms
DAO-IN-2;79793-31-2;AKOS BB-9991;CHEMBRDG-BB 4012315;D-Amino Acid Oxidase Inhibitor;Thieno[2,3-b]pyrrole-5-carboxylic acid;4-Thieno[3,2-b]pyrrole-5-carboxylic acid;4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID;4H-thieno[2,3-d]pyrrole-5-carboxylic acid;4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE)
CBNumber:
CB9349944
Molecular Formula:
C7H5NO2S
Molecular Weight:
167.19
MDL Number:
MFCD07368542
MOL File:
39793-31-2.mol
MSDS File:
SDS
Last updated:2023-07-14 17:43:26
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4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Properties

Melting point 180 °C
Boiling point 437.4±25.0 °C(Predicted)
Density 1.609
storage temp. Sealed in dry,2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form Beige solid
pka 4.36±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-26-36/37/39
WGK Germany  3
NFPA 704
1
2 0

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 760250 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 39793-31-2 500mg $31.6 2023-06-20 Buy
Sigma-Aldrich 138000 D-Amino Acid Oxidase Inhibitor 39793-31-2 50mg $110 2023-01-07 Buy
Alfa Aesar H58200 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97% 39793-31-2 1g $201.65 2024-03-01 Buy
Alfa Aesar H58200 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97% 39793-31-2 5g $770 2021-12-16 Buy
Cayman Chemical 23894 D-Amino Acid Oxidase Inhibitor ≥98% 39793-31-2 250mg $68 2024-03-01 Buy
Product number Packaging Price Buy
760250 500mg $31.6 Buy
138000 50mg $110 Buy
H58200 1g $201.65 Buy
H58200 5g $770 Buy
23894 250mg $68 Buy

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 2556, 1957 DOI: 10.1021/ja01567a053

General Description

A cell-permeable thienopyrrole compound that potently inhibits the cellular activity of transfected D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) in CHO cells (IC50 against human and rat DAO = 145 and 114 nM, respectively), while exhibiting no activity towards D-aspartate oxidase (DDO; IC50 >5 μM), P450 enzymes CYP3A4/2D6/3C9 (IC50 >10 μM), and a panel of over 150 other enzymes, receptors, and ion channels. Although in vivo treatment of Compound 8 (200 mg/kg, i.p.) is shown to effectively inhibit DAO activity in rat brain and kidney (by 96% and 80%, respectively), the resulting D-serine concentration increase in the periphery and central nervous system appears to be far from sufficient to produce adequate antipsychotic and cognitive enhancing effects.

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Suppliers

Global( 82)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Changzhou PBpharmaceutical R&D Co.,Ltd 		0519-83990708 info@pbpharm.com CHINA 498 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9991 58
Golden Pharma Co., Limited 		+undefined18958062155 sales@zjgoldpharm.com China 5905 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503259 +86-19930503259 cherry@crovellbio.com China 18451 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
career henan chemical co 		58
Changzhou PBpharmaceutical R&D Co.,Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Coresyn Pharmatech Co., Ltd. 		58
Golden Pharma Co., Limited 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58

View Lastest Price from 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID pictures 2019-07-06 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
39793-31-2
 US $1.00 / kg 1kg 98% 200kg Career Henan Chemical Co

39793-31-2(4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID)Related Search:

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Ethyl 4H-thieno[2,3-d]pyrrole-5-carboxylate 3-BROMO-4(H)-THIENO[3,2-B]PYRROLE-5-CARBOXYLICACID 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID ETHYL ESTER METHYL 2-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLATE ETHYL 2-CHLORO-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLATE
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2-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID METHYL 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLATE 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID

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4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE) Thieno[2,3-b]pyrrole-5-carboxylic acid 4H-thieno[2,3-d]pyrrole-5-carboxylic acid D-Amino Acid Oxidase Inhibitor 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID AKOS BB-9991 CHEMBRDG-BB 4012315 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem 79793-31-2 4-Thieno[3,2-b]pyrrole-5-carboxylic acid 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid (6CI, 7CI, 9CI, ACI) DAO-IN-2 39793-31-2 79793-31-2 C7H5NO2S