2,6-다이메틸아닐린

2,6-다이메틸아닐린
2,6-다이메틸아닐린 구조식 이미지
카스 번호:
87-62-7
한글명:
2,6-다이메틸아닐린
동의어(한글):
2,6-다이메틸아닐린;2,6-자일리딘;2,6-다이메틸아닐린;o-자일리딘;벤젠아민,2,6-다이메틸-
상품명:
2,6-Dimethylaniline
동의어(영문):
2,6-XYLIDINE;2,6-Dimethylbenzenamine;xylylamine;2,6-Xylidin;2,6-dimethylphenylamine;2,6-Dimethyl-phenylamine;2,6-DMA;NSC 7098;ai3-52358;NCI-C56188
CBNumber:
CB8327518
분자식:
C8H11N
포뮬러 무게:
121.18
MOL 파일:
87-62-7.mol
MSDS 파일:
SDS

2,6-다이메틸아닐린 속성

녹는점
10-12 °C(lit.)
끓는 점
216 °C
밀도
0.984 g/mL at 25 °C(lit.)
증기압
<0.01 mm Hg ( 20 °C)
굴절률
n20/D 1.560(lit.)
인화점
196 °F
저장 조건
Store below +30°C.
용해도
13g/L
물리적 상태
액체
산도 계수 (pKa)
3.89(at 25℃)
색상
투명한 노란색에서 적갈색까지
pH 범위
12.5
수소이온지수(pH)
12.5 (100g/l, H2O, 20℃)
폭발한계
1.3-6.9%(V)
수용성
7.5g/L(20℃)
Merck
14,10084
BRN
636332
안정성
공기에 민감한, 흡습성
LogP
1.840
CAS 데이터베이스
87-62-7(CAS DataBase Reference)
IARC
2B (Vol. 57) 1993
NIST
Benzenamine, 2,6-dimethyl-(87-62-7)
EPA
2,6-Xylidine (87-62-7)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N,T
위험 카페고리 넘버 20/21/22-37/38-40-51/53
안전지침서 23-25-36/37-61
유엔번호(UN No.) UN 1711 6.1/PG 2
WGK 독일 2
RTECS 번호 ZE9275000
F 고인화성물질 8
자연 발화 온도 490 °C
TSCA Yes
위험 등급 6.1
포장분류 II
HS 번호 29214910
유해 물질 데이터 87-62-7(Hazardous Substances Data)
독성 LD50 orally in Rabbit: 1290 mg/kg
기존화학 물질 KE-11202
그림문자(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
H351 암을 일으킬 것으로 의심됨 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 발암성 물질 구분 2 경고 P201, P202, P281, P308+P313, P405,P501
H411 장기적 영향에 의해 수생생물에 유독함 수생 환경유해성 물질 - 만성 구분 2
예방조치문구:
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
NFPA 704
1
2 0

2,6-다이메틸아닐린 MSDS


2,6-Dimethylaniline

2,6-다이메틸아닐린 C화학적 특성, 용도, 생산

화학적 성질

clear yellow to red-brown liquid

용도

2,6-Dimethylaniline is used in pharmaceuticals, as dye intermediates and in organic synthesis. It is also used in the production of antioxidants, agricultural, pharmaceutical, rubber chemicals and other target organic molecules.

정의

ChEBI: 2,6-dimethylaniline is a primary arylamine that is aniline in which the hydrogens at the 2- and 6-positions are replaced by methyl groups. It is used in the production of some anasthetics and other chemicals. It is a drug metabolite of lidocaine (local anasthetic). It has a role as a carcinogenic agent and a drug metabolite. It is a primary arylamine and a dimethylaniline.

제조 방법

2,6-Dimethylaninile is prepared by nitration of xylene and reduction, followed by removal of the 2,4-isomer by formation of the acetate salt, removal of the 2,5-isomer by formation of the hydrochloride salt, and recovery of the 2,6-isomer by sublimation (US National Library of Medicine, 1992a).
2,6-Dimethylaniline is produced by one company each in Japan, Switzerland and the USA and by three companies in Germany (Chemical Information Servces, 1991).

일반 설명

A liquid. Toxic by ingestion, inhalation and skin absorption. Slightly soluble in water. Used in pharmaceuticals, as dye intermediates and organic syntheses.

공기와 물의 반응

Slightly soluble in water.

반응 프로필

2,6-Dimethylaniline reacts with strong oxidizing agents [Handling Chemicals Safely 1980 p. 964]. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

건강위험

May be fatal if inhaled, swallowed or absorbed through skin. Vapor or mist irritating to the eyes, mucous membranes and upper respiratory tract; causes skin irritation. Absorption into body leads to the formation of methemoglobin which, in sufficient concentration, may cause cyanosis. Onset may be delayed 2-4 hours or longer. Exposure can cause nausea, dizziness, headache, damage to the eyes, and blood effects.

화재위험

Special Hazards of Combustion Products: Container explosion may occur under fire conditions. Emits toxic fumes under fire conditions.

Safety Profile

Suspected carcinogen. Moderately toxic by ingestion. Mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert vic-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry it over KOH and fractionally distil. The acetyl derivative has m 177o, the benzoyl derivative has m 168o, and the picrate has m 180o. [Beilstein 12 H 1107, 12 IV 2521.]

2,6-다이메틸아닐린 준비 용품 및 원자재

원자재

준비 용품


2,6-다이메틸아닐린 공급 업체

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