프로판디올(S-1,2)
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프로판디올(S-1,2) 속성
- 녹는점
- -59 °C
- 알파
- 16 º (c=neat)
- 끓는 점
- 186-188 °C765 mm Hg(lit.)
- 밀도
- 1.036 g/mL at 20 °C(lit.)
- 굴절률
- n
20/D 1.432(lit.)
- 인화점
- 225 °F
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- Miscible with acetone, chloroform, ethanol (95%), glycerin, and water; soluble at 1 in 6 parts of ether; not miscible with light mineral oil or fixed oils, but will dissolve some essential oils.
- 산도 계수 (pKa)
- 14.49±0.20(Predicted)
- 물리적 상태
- 액체
- 색상
- 무색의
- Specific Gravity
- 1.04
- optical activity
- [α]20/D +16.5°, neat
- 폭발한계
- 2.6-12.6%(V)
- 수용성
- 녹는
- 감도
- Hygroscopic
- Merck
- 14,7855
- BRN
- 1718871
- 안정성
- 휘발성 물질
- CAS 데이터베이스
- 4254-15-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-22 | ||
| 안전지침서 | 24/25-36/37/39-26 | ||
| WGK 독일 | 1 | ||
| HS 번호 | 29053200 |
프로판디올(S-1,2) C화학적 특성, 용도, 생산
화학적 성질
Colorless to light yellow liqui용도
(S)-(+)-1,2-Propanediol acts as an organic solvent and diluent used in pharmaceutical preparations. It is also used as a chiral synthetic intermediate and substrate for enzyme studies.생산 방법
Propylene is converted to chlorohydrin by chlorine water and hydrolyzed to 1,2-propylene oxide. With further hydrolysis, 1,2- propylene oxide is converted to propylene glycol.Pharmaceutical Applications
Propylene glycol has become widely used as a solvent, extractant, and preservative in a variety of parenteral and nonparenteral pharmaceutical formulations. It is a better general solvent than glycerin and dissolves a wide variety of materials, such as corticosteroids, phenols, sulfa drugs, barbiturates, vitamins (A and D), most alkaloids, and many local anesthetics.As an antiseptic it is similar to ethanol, and against molds it is similar to glycerin and only slightly less effective than ethanol. Propylene glycol is commonly used as a plasticizer in aqueous film-coating formulations.
Propylene glycol is also used in cosmetics and in the food industry as a carrier for emulsifiers and as a vehicle for flavors in preference to ethanol, since its lack of volatility provides a more uniform flavor.
저장
At cool temperatures, propylene glycol is stable in a well-closed container, but at high temperatures, in the open, it tends to oxidize, giving rise to products such as propionaldehyde, lactic acid, pyruvic acid, and acetic acid. Propylene glycol is chemically stable when mixed with ethanol (95%), glycerin, or water; aqueous solutions may be sterilized by autoclaving.Propylene glycol is hygroscopic and should be stored in a wellclosed container, protected from light, in a cool, dry place.
비 호환성
Propylene glycol is incompatible with oxidizing reagents such as potassium permanganate.Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (dental preparations; IM and IV injections; inhalations; ophthalmic, oral, otic, percutaneous, rectal, topical, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.프로판디올(S-1,2) 준비 용품 및 원자재
원자재
준비 용품
프로판디올(S-1,2) 공급 업체
글로벌( 352)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18374 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15954 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21687 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8829 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |