(8β)-10-메톡시-1,6-디메틸에르고린-8-메탄올-5-브로모-3-피리딘카복실 에스테르 C화학적 특성, 용도, 생산
화학적 성질
Fine to granular, white or yellowish powder.
용도
Nicergoline is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
생물학적 활성
α -adrenergic, vasodilator. Cognitive enhancer.
Safety Profile
Poison by intravenous
route. Moderately toxic by ingestion and
subcutaneous routes. An experimental
teratogen. Other experimental reproductive
effects. A vasodilator. When heated to
decomposition it emits very toxic fumes of
Brand NOx.
(8β)-10-메톡시-1,6-디메틸에르고린-8-메탄올-5-브로모-3-피리딘카복실 에스테르 준비 용품 및 원자재