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ChemicalBook >> CAS DataBase List >> 4-Chloro-1,2-dihydro-3-(ethoxycarbonyl)-1-methyl-2-oxoquinoline

4-Chloro-1,2-dihydro-3-(ethoxycarbonyl)-1-methyl-2-oxoquinoline

4-Chloro-1,2-dihydro-3-(ethoxycarbonyl)-1-methyl-2-oxoquinoline price.
  • $130 - $2367.75
  • Product name: 4-Chloro-1,2-dihydro-3-(ethoxycarbonyl)-1-methyl-2-oxoquinoline
  • CAS: 75483-04-4
  • MF: C13H12ClNO3
  • MW: 265.69
  • EINECS:
  • MDL Number:MFCD00634787
  • Synonyms:4-Chloro-1,2-dihydro-3-(ethoxycarbonyl)-1-methyl-2-oxoquinoline;Ethyl 4-chloro-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxylate;4-Chloro-1,2-dihydro-1-methyl-2-oxo-3-quinolinecarboxylic acid ethyl ester;AI-1;Nrf2 Activator II, AI-1 ;AI-1 (Nrf2 acticatior AI-1);Nrf2 Activator II, AI-1 - CAS 75483-04-4 - Calbiochem;AI-1 >=98% (HPLC)
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • Sigma-Aldrich
Package
  • 5mg
  • 25mg
  • 500mg
  • 1G
  • 5G
  • 10G
  • ManufacturerAK Scientific
  • Product number8525BA
  • Product descriptionEthyl4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
  • Packaging500mg
  • Price$374
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0007319
  • Product descriptionETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00%
  • Packaging1G
  • Price$1004.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0007319
  • Product descriptionETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00%
  • Packaging5G
  • Price$1547.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0007319
  • Product descriptionETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00%
  • Packaging10G
  • Price$2367.75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM223206
  • Product descriptionEthyl4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 95%
  • Packaging5g
  • Price$711
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11062074
  • Product descriptionEthyl4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 95+%
  • Packaging5g
  • Price$752
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0009
  • Product descriptionAI-1 ≥98% (HPLC)
  • Packaging5mg
  • Price$130
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number492041
  • Product descriptionNrf2 Activator II, AI-1
  • Packaging25mg
  • Price$208
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8525BA Ethyl4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 500mg $374 2021-12-16 Buy
American Custom Chemicals Corporation HCH0007319 ETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00% 1G $1004.85 2021-12-16 Buy
American Custom Chemicals Corporation HCH0007319 ETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00% 5G $1547.7 2021-12-16 Buy
American Custom Chemicals Corporation HCH0007319 ETHYL 4-CHLORO-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLATE 95.00% 10G $2367.75 2021-12-16 Buy
Chemenu CM223206 Ethyl4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 95% 5g $711 2021-12-16 Buy
Crysdot CD11062074 Ethyl4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 95+% 5g $752 2021-12-16 Buy
Sigma-Aldrich SML0009 AI-1 ≥98% (HPLC) 5mg $130 2022-05-15 Buy
Sigma-Aldrich 492041 Nrf2 Activator II, AI-1 25mg $208 2024-03-01 Buy

Properties

Melting point :90-92 °C
Boiling point :358.7±42.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :-2.22±0.60(Predicted)
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

AI-1 (75483-04-4) is a novel antioxidant response element (ARE) activator which activates Nrf2 by covalently modifying Keap1 (Kelch-like ECH-associated protein 1) a negative regulator of Nrf2. Modification of Cys151 of Keap1 by AI-1 disrupts the ability of Keap1 to serve as an adaptor for Cul3-Keap1 ubiquitin ligase complex, thereby stabilizing and inducing transcriptional activation of Nrf2. AI-1 is a useful pharmacological tool for probing the involvement of Nrf2 in cellular physiology.1?Cell permeable.

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Suppliers and manufacturers

Energy Chemical Abmole Bioscience Inc. Shanghai Haohong Scientific Co., Ltd. Nanjing Shizhou Biology Technology Co.,Ltd