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N,N-Dimethylacetoacetamide

N,N-Dimethylacetoacetamide Suppliers list
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008657128800458; +8615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:Fanda DMAA
CAS:2044-64-6
Purity:80% Package:200kg (Fandachem) Remarks:Fandachem DMAA 80% water solution manufacturer
Company Name: LY Global chemicals co.,ltd .
Tel: +8618939937369
Email: info@lychems.cn
Products Intro: Product Name:N,N-Dimethylacetoacetamide
CAS:2044-64-6
Purity:98.0% Package:1kg;0.00;USD|25kg;0.00;USD
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:N,N-Dimethylacetoacetamide
CAS:2044-64-6
Purity:99% Package:25KG
Company Name: Hebei Guanlang Biotechnology Co,.LTD
Tel: +8619930503252
Email: daisy@crovellbio.com
Products Intro: Product Name:N,N-Dimethylacetoacetamide
CAS:2044-64-6
Purity:99% Package:1KG;5USD|10KG;3USD|50KG;2USD
Company Name: Henan Fengda Chemical Co., Ltd
Tel: +86-371-86557731 +86-13613820652
Email: info@fdachem.com
Products Intro: Product Name:N,N-Dimethylacetoacetamide
CAS:2044-64-6
Purity:98% Package:1KG;5USD|1000KG;0.1USD

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N,N-Dimethylacetoacetamide Basic information
Description Application
Product Name:N,N-Dimethylacetoacetamide
Synonyms:Acetylacetamide, N,N-dimethyl-;Butanamide, N,N-dimethyl-3-oxo-;Butanamide,N,N-dimethyl-3-oxo-;Dimethylamid kyseliny acetoctove;dimethylamidkyselinyacetoctove;Acetoacetdimethylamide;N,N-Dimethylacetoacetamide (approx. 80% in water);N,N-Dimethylacetoacetamide (approx. 95% in water)
CAS:2044-64-6
MF:C6H11NO2
MW:129.16
EINECS:218-059-8
Product Categories:API
Mol File:2044-64-6.mol
N,N-Dimethylacetoacetamide Structure
N,N-Dimethylacetoacetamide Chemical Properties
Melting point -55 °C
Boiling point 105 °C(lit.)
density 1.067 g/mL at 25 °C
vapor pressure 19.84hPa at 25℃
refractive index n20/D 1.447
Fp 252 °F
storage temp. Inert atmosphere,Room Temperature
solubility H2O: soluble
pka12.82±0.46(Predicted)
form clear liquid
color APHA: ≤350
Water Solubility hydrolysis SLOWLY
BRN 1755038
LogP0.91 at 25℃
CAS DataBase Reference2044-64-6(CAS DataBase Reference)
NIST Chemistry ReferenceN,N-Dimethylacetoacetamide(2044-64-6)
EPA Substance Registry SystemButanamide, N,N-dimethyl-3-oxo- (2044-64-6)
Safety Information
Hazard Codes N
Risk Statements 36/37/38-51/53
Safety Statements 26-36-61
RIDADR UN 3082 9 / PGIII
WGK Germany -
RTECS AK4035000
HS Code 2924.19.1150
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
N,N-Dimethylacetoacetamide Usage And Synthesis
DescriptionN,N-dimethylacetoacetamide is a clear, colorless to yellow liquid used as a general purpose, low color generating co-promoter for many unsaturated polyester (FRP) resin formulations. It is also used in the production of low VOC unsaturated polyester (FRP) systems for coatings and as an intermediate for the production of insecticides.
ApplicationN,N-Dimethylacetylacetamide is an organic intermediate that can be used to prepare thioamide compounds. As an important thiocarboxylic acid derivative, thioamide compounds have received extensive attention in pharmaceutical synthesis, chemical engineering and related fields. Thioamide and its derivatives have a wide range of applications in analysis, materials, and electrochemistry. They are not only used in the production of polymerization inhibitors, catalysts, stabilizers, pesticides, etc., but also in the production of pharmaceutical raw materials, vulcanizing agents, and chemicals. Coupling reagents, collectors, etc.
Chemical PropertiesClear, colorless to yellow liquid
UsesN,N-Dimethylacetamide is used as intermediate for the production of insecticides, e.g. dicrotophos and as a promoter in unsaturated polyester resins. Product Data Sheet
UsesN,N-Dimethyl-3-oxobutanamide is used as a reactant in the asymmetric hydrogenation of functionalized ketones in presence of chiral bis(diphenylphosphino)binaphthyl ruthenium complex.
General DescriptionThe product is an 80% solution of N,N-dimethylacetoacetamide (DMAA) in water.
Flammability and ExplosibilityNon flammable
ToxicologyN,N-Dimethylacetoacetamide (DMAAm) is a β-dicarbonyl compound that is utilized as a co-promoter in the production of unsaturated polyester resins used in coating materials and as an industrial intermediate in insecticide synthesis. Patents have also been issued for its use in hair colorants. However, DMAAm had limited toxicology and information available. DMAAm appears to have low toxicity in rodents. Smyth et al. reported an oral LD50 in male CarworthWistar rats of 22.6mL/kg (estimated to be approximately 19.8g/kg) and a dermal LD50 in male New Zealand rabbits of 14.1mL/kg (12.4g/kg) (single 8-h exposure). Oral gavage administration of DMAAm did not result in any mortality in rats (strain and gender not reported) at doses up to 3.2g/kg. DMAAm has been identified as a hydrolytic product and a degradation product of the insecticide dicrotophos ((dimethoxyphosphinyloxy)-N, N-dimethylcis-crotonamide) in soil, but was not found as a urinary metabolite of this insecticide in rats[1].
References[1] Timothy Fennell. “Disposition and metabolism of N,N-dimethylacetoacetamide in male F344 and Wistar-Han rats and female B6C3F1 mice.” Xenobiotica 41 11 (2011): 1013–20.
N,N-Dimethylacetoacetamide Preparation Products And Raw materials
Preparation ProductsN,N-DIMETHYL-2-CHLOROACETOACETAMIDE
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