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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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Product Name:(+)-AJ 76 hydrochloride;(1S,2R)-cis-5-Methoxy-1-Methyl-2-(N-propylaMino)tetralinhydrochloride
CAS:85379-09-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:(+)-AJ 76 hydrochloride
CAS:85379-09-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | (+)-AJ 76 HYDROCHLORIDE Basic information |
| Product Name: | (+)-AJ 76 HYDROCHLORIDE | | Synonyms: | AJ-76;(+)-AJ76 HCL;(+)-AJ 76 HYDROCHLORIDE;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE;(1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride;5-methoxy-1-methyl-2-(n-propylamino)tetralin;(1S)-1,2,3,4-Tetrahydro-5-methoxy-1α-methyl-N-propyl-2α-naphthalenamine | | CAS: | 85379-09-5 | | MF: | C15H23NO | | MW: | 233.35 | | EINECS: | | | Product Categories: | | | Mol File: | 85379-09-5.mol |  |
| | (+)-AJ 76 HYDROCHLORIDE Chemical Properties |
| Boiling point | 345.3±42.0 °C(Predicted) | | density | 1.00±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble to 10 mM in H2O | | form | White crystalline solid. | | pka | 10.28±0.40(Predicted) |
| | (+)-AJ 76 HYDROCHLORIDE Usage And Synthesis |
| Uses | (+)-AJ 76 Hydrochloride was used in asymmetric synthesis of methoxymethyl(di-n-propylamino)tetralin hydrochloride. | | Definition | ChEBI: A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21
nd 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively). | | Biological Activity | Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively). | | references | [1]. kullingsjö h, carlsson a, svensson k. effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-aj76, on locomotor activity and brain da metabolism in the rat. eur j pharmacol, 1991, 205(3): 241-246.
[2]. piercey mf, lum jt, hoffmann we, et al. antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-aj76 and (+)-uh232. brain res, 1992; 588(2): 217-222.
[3]. waters n, hansson l, löfberg l, et al. intracerebral infusion of (+)-aj76 and (+)-uh232: effects on dopamine release and metabolism in vivo. eur j pharmacol, 1994, 251(2-3): 181-190. |
| | (+)-AJ 76 HYDROCHLORIDE Preparation Products And Raw materials |
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