API

Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.

Oleamide: natural occurrence, biologic actions and biosynthesis

Oleamide is a natural compound found in biological fluids that inhibits gap junction communication by interacting with receptors, and its biosynthesis involves multiple mechanisms.

Dec 21,2023  API

How to determine the polarity of oxygen?

Oxygen is an oxidizing agent that forms oxides with multiple compounds readily. There are many known allotropes of oxygen, out of which O2 is the most stable one.

Dec 20,2023  API

2,3-Dichloropyridine solubility in 14 pure solvents

The increase in solubility of 2,3-dichloropyridine (23DCP) in 14 pure solvents is positively correlated with temperature. This is an endothermic and entropy increasing solvation process.

Dec 20,2023  API

The Synthetic method and Drug interaction of Sarecycline

Sarecycline Hydrochloride is the hydrochloride form of sarecycline. Sarecycline is a novel tetracycline-derived drug, specifically designed for acne.

Dec 20,2023  API

Is 8-Hydroxyquinoline a corrosion inhibitor?

8-hydroxyquinoline can be used as a raw material for the synthesis of corrosion inhibitors. And studies have reported the corrosion inhibition of 8-hydroxyquinoline derivatives on N80 steel in 1 M hyd

Dec 20,2023  API

Polarity of Carbon tetrachloride(CCl4)

CCl4 has a dipole moment of 0 and is a non-polar molecule.

Dec 20,2023  API

Is XeF2 a polar or non-polar molecule?

XeF2 is a non-polar molecule because the fluorine molecules on either side of the central atom do not have dipole moments and therefore have no polarity.

Dec 20,2023  API

Introduction to the synthesis method of Baloxavir marboxil

Baloxavir is a novel cap-dependent endonuclease inhibitor that blocks influenza virus proliferation by inhibiting the initiation of mRNA synthesis.

Dec 20,2023  API

Propylparaben: A Common Antimicrobial and Preservative Chemical Found in Personal Care Products and Food

Propylparaben, a paraben compound, is widely used for its antimicrobial and preservative properties in various consumer products. The majority of it is excreted as non-specific metabolites.

Dec 20,2023  API

4,4-Piperidinediol hydrochloride: synthesis and applications in organic synthesis

The synthesis of 4,4-Piperidinediol hydrochloride involves C-H and C-C bond functionalizations. It serves as a building block for bis-bispidine tetraazamacrocycles and pharmaceutical compounds.

Dec 20,2023  API
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