Potassium Sorbate: Versatile and Effective Food Preservative with Alkylating Potential
Potassium sorbate is a commonly used food preservative with low toxicity and high solubility and exhibits alkylating potential, but further research is needed on its implications for human health.
Jan 5，2024 API
The Use of Bromobenzene as a Solvent
Bromobenzene is the simplest member of the class of bromobenzenes, it has a role as a non-polar solvent. Bromobenzene shows different bromination selectivity in polar solvents containing ionic liquid.
Jan 5，2024 Organic Chemistry
A relaxed-state (R-state) stabilizer of hemoglobin: Voxelotor
Voxelotor, also known as GBT440, is a relaxed-state (R-state) stabilizer of hemoglobin developed by Global Blood Therapeutics and approved by the USFDA for treating sickle cell disease.
Jan 5，2024 API
Synthesis of Surufatinib
Surufatinib is synthesised from dichloropyrimidine and hydroxyindole by substitution reaction. This process requires the participation of Surufatinib Amine.
Jan 5，2024 Inhibitors
The Synthesis method of Esaxerenone
Esaxerenone, a novel, nonsteroidal, selective mineralocorticoid receptor antagonist (MRA) discovered by Exelixis and developed by Daiichi Sankyo, was approved in Japan to treat hypertension.
Jan 5，2024 API
How is Selumetinib Sulfate Synthesised?
Selumetinib Sulfate was prepared by a two-step chemical reaction by first synthesising Selumitinib Benzimidazole intermediates using 2,3,4-trifluorobenzoic acid as starting material.
Jan 5，2024 Inhibitors
Selpercatinib: Synthesis and Description
Selpercatinib (LOXO-292) is synthesised using sulfonyl chloride as a raw material by chemical reaction.
Jan 5，2024 Inhibitors
A brief introduction to triclabendazole
Triclabendazole, also known as CGA 89317 or CGP 23030, is an orally bioavailable anthelmintic against infections caused by Fasciola species.
Jan 5，2024 API
How is Sacituzumab Govitecan Synthesised?
The overall synthetic strategy for the preparation of sacituzumab govitecan inherently consists of three separate sequential components, construction of the payload (SN-38) followed by appendage with
Jan 5，2024 Drugs
β-Carotene: Dietary Sources and Benefits
β-Carotene is found in richer sources, mostly in brightly coloured fruits and vegetables such as carrots, spinach, kale, tomatoes, sweet potatoes, broccoli, onions, peppers, cantaloupe and apricots.
Jan 5，2024 Vitamins and Minerals medicines