A material with many uses: Natural rubber
Natural rubber has good dielectric properties, excellent resilience, an elevated damping capacity, and good tear resistance.
Jan 16，2024 Plant extracts
Silicon Nitride: General Properties; Industrial Preparation and Grades
Silicon nitride has been used extensively in a number of other industrial applications, such as engine components, bearings, and cutting tools.
Jan 16，2024 API
Abrocitinib: Synthesis and Application
Abrocitinib is synthesised using ketoester as a raw material by chemical reaction. Abrocitinib is an orally available small-molecule Janus Kinase 1 (JAK1) inhibitor developed by Pfizer and approved i
Jan 16，2024 Inhibitors
The introduction of Siponimod
Siponimod is an oral selective sphingosine 1-phosphate receptor subtypes 1 and 5 (S1PR1,5) modulator being developed by Novartis Pharmaceuticals for the treatment of multiple sclerosis (MS) and intrac
Jan 16，2024 API
Odevixibat: Synthesis and Application
Odevixibat is synthesised in two steps by chemical reaction using enfumafungin as a raw material.
Jan 16，2024 Inhibitors
How is Fosdenopterin synthesised?
The synthesis of Fosdenopterin starts with d-galactose as the starting material and begins with the synthesis of the core structure, which is finally completed by vortex oxidation of secondary alcohol
Jan 16，2024 Drugs
How to synthesize Sotagliflozin?
Sotagliflozin (LX-4211) is a dual sodium-glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the treatment of both type 1 (T1D) and type 2 diabetes (T2D).
Jan 16，2024 API
One of the SGLT2 inhibitors: ReMogliflozin etabonate
Remogliflozin etabonate (RE) is the prodrug of remogliflozin, a selective sodium?glucose cotransporter subtype 2 (SGLT2) inhibitor discovered by Kissei Pharmaceutical.
Jan 16，2024 API
Crizotinib: clinical activity, relapses and mechanisms of resistance
Crizotinib shows clinical activity in ALK+ NSCLC. Relapses occur within a year, CNS-only or oligoprogression. Resistance mechanisms include ALK mutations, copy number alterations and bypass tracks.
Jan 16，2024 API
Pterostilbene in Cancer Therapy
Pterostilbene shows promise as a cancer therapy agent. It inhibits cell proliferation and induces apoptosis in breast and cervical cancers, targeting key proteins and cancer stem cells.
Jan 16，2024 API