How is Filgotinib synthesised?
Filgotinib is prepared using 2-aminopyridine as raw material by condensation, cyclisation, coupling and other reactions.
Dec 27，2023 Inhibitors
Poly(methylhydrosiloxane): A Versatile Silicone Oil with Applications in Chemical Synthesis
Poly(methylhydrosiloxane) is a versatile silicone oil used in waterproof coatings, organic synthesis, catalysis, and protective applications in biomedical and electronic fields.
Dec 27，2023 API
The Applications and Safety Considerations of 2-Butene-1,4-diol in Various Industries
2-Butene-1,4-diol is a versatile compound with moderate hydrophilicity used in alkyd resins, plasticizers, nylon, and pharmaceuticals. However, it can be harmful, causing irritation.
Dec 27，2023 API
New Study Reveals Genetic Polymorphisms Affecting Metformin Efficacy
Metformin's pharmacokinetics involve active cellular uptake through transporters. Genetic polymorphisms in cation transporters influence its effectiveness and clearance.
Dec 27，2023 API
What is Apalutamide
Apalutamide is a next-generation oral androgen receptor (AR) inhibitor that Janssen is developing for the treatment of prostate cancer.
Dec 26，2023 Inhibitors
A cinacalcet analog-Evocalcet
Evocalcet, a novel oral calcimimetic agent, is an allosteric modulator that acts on the calcium-sensing receptors on the membrane of parathyroid cells to suppress parathyroid hormone (PTH) secretion.
Dec 26，2023 Inhibitors
Synthesis of Delgocitinib
Delgocitinib is synthesised using bromolactone as raw material by chemical reaction.
Dec 26，2023 Inhibitors
The synthesis method of Fostamatinib
Fostamatinib is an inhibitor of spleen tyrosine kinase (SYK), a key regulator of signal transduction pathways involved in various autoimmune diseases.
Dec 26，2023 API
Benefits Of Phytosphingosine For Skin
Phytosphingosine (PHS) is a sphingoid critical component of phytoceramides NP, AP, and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differe
Dec 26，2023 Biochemical Engineering
The uses of Tetrakis (hydroxymethyl) Phosphonium Chloride
THPC is formed by treating phosphine with formaldehyde in the presence of hydrogen chloride and is used as an ingredient in flame-retardant chemicals.
Dec 26，2023 Chemical Reagents