Borofalan (10B): Synthesis and Introduction
Borofalan (10B) is synthesised using (S)-4-iodophenylalanine as raw material by chemical reaction.
Dec 29，2023 Drugs
Tert-Butyl methyl ether：Uses and Polarity
Tert-Butyl methyl ether (MTBE) has low solubility and is a non-polar solvent. It has a polarity index of 2.5, a boiling point of 55.3°C, a viscosity of 0.27 (20°C), a refractive index of 1.369, and a
Dec 29，2023 API
Sodium pyruvate：a crucial role in cellular metabolism
Sodium pyruvate: crucial in cellular metabolism, used in culture media, its synthesis involves careful steps, and safety protocols must be followed.
Dec 29，2023 Chemical Reagents
Tofacitinib：a versatile JAK Inhibitor in autoimmune conditions
Tofacitinib, a JAK inhibitor, treats rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis by modulating immune signaling pathways.
Dec 29，2023 Drugs
D-Galactose: Versatile Sources, Applications, and Considerations for Toxicity
D-Galactose can be obtained from terrestrial plants, and macroalgae and has versatile applications, but its toxicity should be considered in metabolic disorders and excessive intake.
Dec 29，2023 API
Iron oxide nanoparticles in photothermal therapy
Iron oxide nanoparticles are promising for cancer treatment via photothermal therapy due to their unique properties, biocompatibility, and ease of modification.
Dec 29，2023 API
The synthesis method of Ivosidenib
Ivosidenib is a first-in-class, oral small molecule, potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1).
Dec 28，2023 Inhibitors
How to synthesize Glasdegib?
Glasdegib was approved in 2018 for the treatment of newly diagnosed acute myeloid leukemia (AML) patients at least 75 years of age who are not appropriate candidates for intensive induction chemothera
Dec 28，2023 API
The Pharmacodynamics and Synthetic method of Gilteritinib
Gilteritinib, an oral inhibitor of FMS‐like tyrosine kinase 3 (FLT3), is a standard treatment for FLT3‐mutated acute myeloid leukemia.
Dec 28，2023 API
4-Formylbenzoic Acid: Versatile Building Block for Biomedical Applications with Catalyst Properties
4-Formylbenzoic acid is a white crystalline powder synthesized by the aerobic oxidation of aldehydes to carboxylic acids and serves as a catalyst for versatile biomedical hydrogels.
Dec 28，2023 API