How Abemaciclib works in treating breast cancer
Preclinical studies have shown that continuous inhibition of CDK4/6 by abemaciclib inhibits phosphorylation of the retinoblastoma protein, which becomes inactivated.
Nov 10，2023 Drugs
Ginsenoside Rg3: mechanism of action, pharmacodynamic and safety
Ginsenoside Rg3 inhibits angiogenesis through VEGF/VEGFR2 modulation and shows safe profiles in studies.
Nov 10，2023 API
2-Anilino-6-dibutylamino-3-methylfluoran: properties, applications and safety
2-Anilino-6-dibutylamino-3-methylfluoran is a valuable component for light-driven phase change materials with temperature-control capabilities, but proper safety precautions must be taken.
Nov 10，2023 API
PIPES: properties, applications and safety
PIPES is a versatile buffering agent for maintaining pH stability, widely used in biological and chemical research.
Nov 10，2023 API
What is the clinical efficacy of Baloxavir marboxil
A single oral dose of baloxavir marboxil in tablet form improves medication adherence and rapidly reduces viral titres in paediatric influenza patients
Nov 10，2023 Drugs
Vonoprazan FuMarate for the treatment of gastric ulcer and Helicobacter pylori infection disease
Vonoprazan fumarate, a potassium-competitive acid blocker(P-CAB), produces a stronger acid-inhibitory effect than proton pump inhibitors (PPIs).
Nov 10，2023 Drugs
Is Resveratrol safety？
Resveratrol is a phytoalexin found in over 300 edible plants, including grapes, berries, and peanuts.
Nov 10，2023 API
Delta-valerolactone: properties and applications
Delta-Valerolactone exhibits unique properties that make it suitable for various applications, including drug-carrier systems and the preparation of functional polyesters.
Nov 10，2023 API
The effect of Minoxidil on hair
Minoxidil is a cosmetic drug recognized as a mitogenic agent, which may be potential mutagenic and carcinogenic agent.
Nov 10，2023 API
Use of the anti-HIV drug (Dolutegravir sodium)
Dolutegravir sodium is an oral, World Health Organisation-recommended first-line antiretroviral drug that belongs to a class of drugs called HIV integrase inhibitors.
Nov 10，2023 Drugs