Dalbavancin---semisynthetic lipoglycopeptide
Dalbavancin (Zeven, Pfizer Inc.) is a semisynthetic lipoglycopeptide with an extended half-life that enables once-weekly dosing. It has potent in vitro activity against most Gram-positive organisms wi
Mar 10,2022 APIBiosynthesis of Mandelic acid
Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H. It is a white crystalline solid that is soluble in water and polar organic solvents. It is a useful precursor
Mar 10,2022 Biochemical EngineeringWhat is Oritavancin?
Oritavancin is a second-generation lipoglycopeptide antibiotic derived from modifications of chloroeremomycin, a naturally occurring glycopeptide. Structurally, oritavancin is very similar to vancomyc
Mar 10,2022 APISide effects of nitrofurantoin
The sole use of this drug is in the treatment of urinary tract infections, as after oral or intravenous (i.v.). administration, therapeutically active concentrations are attained only in urine. The dr
Mar 10,2022 APIDaptomycin---LY 146032
Daptomycin is more active in vitro than glycopeptides against a wide range of Gram-positive aerobic as well as anaerobic organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and van
Mar 10,2022 APIA lipoglycopeptide antibiotic ---Teicoplanin
Teicoplanin (Targocids) is a lipoglycopeptide antibiotic chemically related to vancomycin, which was obtained by fermenting Actinoplanes teichomyceticus.
Mar 10,2022 APIUses of Furazolidone
This nitrofuran has in vitro activity against S. aureus, S. pyogenes, Enterococcus faecalis, E. coli, Vibrio cholerae, Clostrida spp., Klebsiella, Enterobacter, Salmonella, Shigella, Campylobacter, an
Mar 10,2022 APIWhat is Vancomycin?
Vancomycin was isolated in the Lilly Research Laboratories from Amycolatopsis orientalis (previously designated Streptomyces orientalis and Nocardia orientalis), an organism which was found in soil in
Mar 10,2022 APIAdverse effects of Iclaprim
Iclaprim (previously known as AR-100 and Ro 48-2622) is a new member of the diaminopyrimidine class of antimicrobials, to which trimethoprim also belongs.
Mar 10,2022 InhibitorsSide-effects of Trimetrexate
Trimetrexate is a dihydrofolate reductase inhibitor used primarily as an alternative for treatment of the fungus Pneumocystis jirovecii (carinii) and has also been used in the treatment of cerebral to
Mar 10,2022 API







