Dalbavancin---semisynthetic lipoglycopeptide

Dalbavancin (Zeven, Pfizer Inc.) is a semisynthetic lipoglycopeptide with an extended half-life that enables once-weekly dosing. It has potent in vitro activity against most Gram-positive organisms wi

Mar 10,2022  API

Biosynthesis of Mandelic acid

Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H. It is a white crystalline solid that is soluble in water and polar organic solvents. It is a useful precursor

Mar 10,2022  Biochemical Engineering

What is Oritavancin?

Oritavancin is a second-generation lipoglycopeptide antibiotic derived from modifications of chloroeremomycin, a naturally occurring glycopeptide. Structurally, oritavancin is very similar to vancomyc

Mar 10,2022  API

Side effects of nitrofurantoin

The sole use of this drug is in the treatment of urinary tract infections, as after oral or intravenous (i.v.). administration, therapeutically active concentrations are attained only in urine. The dr

Mar 10,2022  API

Daptomycin---LY 146032

Daptomycin is more active in vitro than glycopeptides against a wide range of Gram-positive aerobic as well as anaerobic organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and van

Mar 10,2022  API

A lipoglycopeptide antibiotic ---Teicoplanin

Teicoplanin (Targocids) is a lipoglycopeptide antibiotic chemically related to vancomycin, which was obtained by fermenting Actinoplanes teichomyceticus.

Mar 10,2022  API

Uses of Furazolidone

This nitrofuran has in vitro activity against S. aureus, S. pyogenes, Enterococcus faecalis, E. coli, Vibrio cholerae, Clostrida spp., Klebsiella, Enterobacter, Salmonella, Shigella, Campylobacter, an

Mar 10,2022  API

What is Vancomycin?

Vancomycin was isolated in the Lilly Research Laboratories from Amycolatopsis orientalis (previously designated Streptomyces orientalis and Nocardia orientalis), an organism which was found in soil in

Mar 10,2022  API

Adverse effects of Iclaprim

Iclaprim (previously known as AR-100 and Ro 48-2622) is a new member of the diaminopyrimidine class of antimicrobials, to which trimethoprim also belongs.

Mar 10,2022  Inhibitors

Side-effects of Trimetrexate

Trimetrexate is a dihydrofolate reductase inhibitor used primarily as an alternative for treatment of the fungus Pneumocystis jirovecii (carinii) and has also been used in the treatment of cerebral to

Mar 10,2022  API
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