| Identification | Back Directory | [Name]
ML-9 HYDROCHLORIDE | [CAS]
105637-50-1 | [Synonyms]
ML-9
ML-9, HCl
ML-9 HYDROCHLORIDE
1-(5-CHLORONAPHTHALENE- SULFONYL)HOMOPIPERAZINE
1-(5-chloronaphthalene-1-sulfonyl)-1H-*hexahydro-
1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HE XAHYDRO-1,
1-(5-CHLORONAPHTHALENE-1-SULFONYL)HOMOPIPERAZINE, HCL
1-(chloronaphthalenesulfonyl)-1H-hexahydrodiazepine HCl
1-(5-CHLORONAPHTHALENESULFONYL)HOMOPIPERAZINE HYDROCHLORIDE
1-[(5-chloro-1-naphthyl)sulfonyl]-1,4-diazepane hydrochloride
1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE
1-(5-chloronaphthalen-1-yl)sulfonyl-1,4-diazepane hydrochloride
1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HCL
1-(5-CHLORONAPHTHALENESULPHONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HYDROCHLORIDE
1-(5-CHLORONAPHTHALENESULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE, HYDROCHLORIDE
1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HYDROCHLORIDE
1H-1,4-Diazepine, 1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-, hydrochloride (1:1) | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C15H18Cl2N2O2S | [MDL Number]
MFCD00065525 | [MOL File]
105637-50-1.mol | [Molecular Weight]
361.29 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
196-200 | [storage temp. ]
2-8°C
| [solubility ]
ethanol: 10 mg/mL
| [form ]
powder
| [color ]
white
|
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant | [Biological Activity]
Selective inhibitor of myosin light chain kinase (MLCK). K i values are 32, 4, and 54 μ M for PKA, MLCK, and PKC respectively. Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca 2+ entry (SOCE). | [storage]
Desiccate at RT |
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