| Identification | Back Directory | [Name]
4-hydroxy Nonenal-d3 | [CAS]
148706-06-3 | [Synonyms]
HNE-D3
4-HNE-D3
4-HYDROXY NONENAL-D3
(E)-4-HYDROXYNONENAL-D3
(+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL
(±)-4-hydroxy-9,9,9-d3-non-2E-enal
(E)-9,9,9-trideuterio-4-hydroxynon-2-enal | [Molecular Formula]
C9H13D3O2 | [MDL Number]
MFCD08062234 | [MOL File]
148706-06-3.mol | [Molecular Weight]
159.24 |
| Hazard Information | Back Directory | [Uses]
4-hydroxy Nonenal-d3 (4-HNF-d3) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE by GC- or LC-mass spectrometry. 4-HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 μM. |
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