| Identification | More | [Name]
3,4,5,2',3',4'-Hexahydroxybenzophenone | [CAS]
52479-85-3 | [Synonyms]
2,3,3',4,4',5'-HEXAHYDROXYBENZOPHENONE
2,3,4,3',4',5'-HEXAHYDROXY BENZOPHENONE
(2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone
3,4,5,2',3',4'-HEXAHYDROXYBENZOPHENONE
EXIFONE
(2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-methanon
4-galloylpyrogallol
adlone
2,3,3'',4,4''-HEXAHYDROBENZOXYPHENONE
Methanone, (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)
(2,3,4-Trihydroxyphenyl)(3,4,5-trihydroxyphenyl) ketone | [EINECS(EC#)]
257-945-9 | [Molecular Formula]
C13H10O7 | [MDL Number]
MFCD00082966 | [Molecular Weight]
278.21 | [MOL File]
52479-85-3.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow amorphous powder | [Melting point ]
245°C | [Boiling point ]
674.6±55.0 °C(Predicted) | [density ]
1.759±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.99±0.40(Predicted) | [color ]
Yellow | [Merck ]
3915 | [CAS DataBase Reference]
52479-85-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RTECS ]
PC4995000 | [Toxicity]
LD50 in rats (g/kg): 0.355 i.p.; 1.425 orally (Gazave) |
| Hazard Information | Back Directory | [Description]
Exifone is a nootropic indicated for the treatment of cognitive dysfunctions in geriatric
patients. Its reported clinical efficacy is ascribed to pharmacological activities including
activation of neuronal oxygen and glucose metabolism, free radical scavenging, and
indirect effects on serotonergic and dopaminergic pathways. | [Chemical Properties]
yellow amorphous powder | [Originator]
Pharmascience (France) | [Uses]
Exifone is a nootropic drug and cognitive enhancing agent. Exifone is a free radical scavenger shown to have protective effects againts Exifone has been shown to antagonize amnesias induced by benzodiazepines in mice. | [Definition]
ChEBI: (2,3,4-trihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone is a member of benzophenones. | [Preparation]
Preparation by condensation of gallic acid with pyrogallol,
? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction);
? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement. | [Brand name]
Adlone |
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