| Identification | More | [Name]
D-alpha-Tocopheryl acetate | [CAS]
58-95-7 | [Synonyms]
(+)-ALPHA-TOCOPHEROL ACETATE
D-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
D-ALFACOL
D-ALPHA-TOCOPHEROL ACETATE
D-ALPHA-TOCOPHERYL ACETATE
D-A-TOCOPHERYL ACETATE
D-CONTOPHERON
D-ECON
D-FERTILVIT
D-TOCOPHEROL ACETATE
D-TOCOPHRIN
D-VITAMIN E ACETATE
TOCOPHERYL ACETATE
VITAMIN E
VITAMIN E ACETATE
VITAMIN E ACETATE (D-FORM)
VITAMIN E ALPHA TOCOPHEROL ACETATE
VITAMINE E-ACETATE
(2r,4’r,8’r)-alpha-tocopherylacetate
(2R,4’R,8’R)-O-Acetyl-α-tocopherol | [EINECS(EC#)]
231-710-0 | [Molecular Formula]
C31H52O3 | [MDL Number]
MFCD00072052 | [Molecular Weight]
472.74 | [MOL File]
58-95-7.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white crystalline solid | [Melting point ]
~25 °C(lit.)
| [alpha ]
3 º (c=2, in ethanol 25 ºC) | [Boiling point ]
224 °C0.3 mm Hg(lit.)
| [density ]
0.953 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.496(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent). | [form ]
oil or semi-solid
| [color ]
yellow
| [Odor]
cryst., odorless | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
<0.1 g/100 mL at 17 ºC | [Merck ]
9495 | [Contact allergens]
Tocopherol and tocopheryl acetate are used mainly as
antioxidants. Tocopheryl acetate, an ester of tocopherol
(vitamin E), can induce allergic contact dermatitis. | [LogP]
12.260 (est) | [CAS DataBase Reference]
58-95-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Vitamin e acetate(58-95-7) | [EPA Substance Registry System]
58-95-7(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
off-white crystalline solid | [Uses]
vitamin E | [General Description]
Odorless off-white crystals. Darkens at 401° F. | [Reactivity Profile]
An ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. | [Air & Water Reactions]
This chemical may be sensitive to prolonged exposure to light and air. . Insoluble in water. | [Fire Hazard]
Flash point data for this chemical are not available. D-ALPHA-TOCOPHERYL ACETATE is probably combustible. | [Definition]
ChEBI: Alpha-Tocopherol acetate is a tocol. | [Biochem/physiol Actions]
α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes. |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
1
| [RTECS ]
GP8280000
| [HS Code ]
29362800 | [Safety Profile]
When heated to
decomposition it emits acrid smoke and
irritating fumes. |
| Questions And Answer | Back Directory | [Description]
D-alpha-tocopheryl acetate is a natural form of vitamin E and it is stable in terms of shelf life. It is probably the best form for people actively trying to prevent heart disease. It is used in the dietary and clinical supplementations.
| [References]
[1] Jack Challem, User’s Guide to Nutritional Supplements, 2003
[2] M. K. Horwitt, Relative biological values of d-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate in man, The American Society for Clinical Nutrition, 1980, vol. 33, 1856-1860
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