| Identification | Back Directory | [Name]
EC 3.4.14.1 | [CAS]
9032-68-2 | [Synonyms]
DPP1
EC 3.4.14.1
CATHEPSIN C
E.C. 3.4.4.9
CATHEPSIN C TYPE X
CATHEPSIN C, BOVINE
Dipeptidyl transferase
DIPEPTIDYL PEPTIDASE I
Dipeptide arylamidase I
DIPEPTIDYL AMINOPEPTIDASE
Native Bovine Cathepsin C
DIPEPTIDYLPEPTIDE HYDROLASE
cathepsin c from bovine spleen
cathepsin C type X: from bovine spleen
CATHEPSIN C, SOLUTION, FROM BOVINE SPLEEN
Dipeptidyl aminopeptidase, Dipeptidyl peptidaseI | [EINECS(EC#)]
232-881-4 | [MDL Number]
MFCD00081490 |
| Hazard Information | Back Directory | [Uses]
The enzyme from Sigma has been used in the activation of granzyme k (Gzmk) precursor from E. coli. Granzymes are granule-stored lymphocyte serine proteases that are implicated in T- and natural killer cell-mediated cytotoxic defense reactions. | [Biochem/physiol Actions]
Cathespin C is a dipeptidyl aminopeptidase that can sequentially remove dipeptides from a peptide chain with an unsubstituted N-terminus. The enzyme exhibits a preference for glycine and proline as N-terminal aminoacids. Substrates that have an N-terminal lysyl or arginyl residue, or a penultimate proryl residue are not targeted by this enzyme. The endopeptidase activity requires the presence of halide ions and sulfydryl activators. |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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SIGMA-RBI
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800 736 3690 (Orders) |
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www.sigma-aldrich.com |
| Company Name: |
Creative Enzymes
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1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
| Company Name: |
Creative Enzymes
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+1 (631) 559-9269 |
| Website: |
www.creative-enzymes.com |
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