化合物UK371804
|
|
- CAS号:
- 256477-09-5
- 英文名:
- UK-371804
- 英文别名:
- UK-371804;Urokinase inhitibor 1;Urokinase inhibitor 1;UK-371804 (Urokinase inhitibor 1);UK 371804,UK-371804,Inhibitor,PAI-1,inhibit,Plasminogen activator inhibitor-1;2-(1-carbamimidamido-4-chloroisoquinoline-7-sulfonamido)-2-methylpropanoic acid;N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine;Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-
- 中文名:
- 化合物UK371804
- 中文别名:
- 化合物UK371804
- CBNumber:
- CB13160423
- 分子式:
- C14H16ClN5O4S
- 分子量:
- 385.83
- MOL File:
- 256477-09-5.mol
|
|
|
化合物UK371804化学性质
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
DMSO:5.0(Max Conc. mg/mL);2.59(Max Conc. mM)
-
|
-
形态:
-
A crystalline solid
-
|
-
颜色:
-
White to off-white
-
|
-
CAS 数据库:
-
256477-09-5
-
|
化合物UK371804性质、用途与生产工艺
UK-371804是尿嘧啶型纤溶酶原激活物 (uPA) 的抑制剂,Ki值为10 nM。
UK-371804 is able to inhibit exogenous uPA in human chronic wound fluid (IC
50
=0.89 μM). UK-371804 has its excellent enzyme potency (K
i
=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
In a porcine acute excisional wound model, following topical delivery, UK-371804 is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. Concentrations of UK-371804 in the dermis are 41.8 μM.
化合物UK371804
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
---|
2024/08/19 | HY-101214 | UK-371804 | | 1 mg | 480元 |
2024/08/19 | HY-101214 | UK-371804 | 256477-09-5 | 5mg | 1200元 |
256477-09-5, 化合物UK371804 相关搜索:
- 抑制剂
- 生物试剂
- C14H16ClN5O4S
- 化合物UK371804
- 256477-09-5
- 2-(1-carbamimidamido-4-chloroisoquinoline-7-sulfonamido)-2-methylpropanoic acid
- UK 371804,UK-371804,Inhibitor,PAI-1,inhibit,Plasminogen activator inhibitor-1
- N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine
- Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-
- UK-371804 (Urokinase inhitibor 1)
- Urokinase inhitibor 1
- Urokinase inhibitor 1
- UK-371804