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영국-371804

영국-371804 구조식 이미지

카스 번호:: 256477-09-5

한글명:: 영국-371804

동의어(한글):: 영국-371804

상품명:: UK-371804

동의어(영문):: UK-371804;Urokinase inhitibor 1;Urokinase inhibitor 1;UK-371804 (Urokinase inhitibor 1);UK 371804,UK-371804,Inhibitor,PAI-1,inhibit,Plasminogen activator inhibitor-1;N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine;Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-

CBNumber:: CB13160423

분자식:: C14H16ClN5O4S

포뮬러 무게:: 385.83

MOL 파일:: 256477-09-5.mol

속성

안전

용도

공급 업체 61

영국-371804 속성

저장 조건: Store at -20°C

용해도: DMSO:5.0(Max Conc. mg/mL);2.59(Max Conc. mM)

물리적 상태: 결정성 고체

색상: White to off-white

CAS 데이터베이스: 256477-09-5

안전

영국-371804 C화학적 특성, 용도, 생산

개요

UK-371804 is a potent and selectiveurokinase-type plasmogen activator (uPA)inhibitor. It has excellent selectivityover tPA, plasmin, Factor IXa and Xa.In vitro, it is able to inhibit exogenous uPA in human chronic wound fluid (IC50=0.89 microM). In vivo, in a porcine acute excisional wound modelfollowing topical delivery, it is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. It has the potential for the treatment of chronic dermal ulcers.

참고 문헌

http://www.dcchemicals.com/product_show-UK_371804.html
http://adisinsight.springer.com/drugs/800026963
Fish, P. V., et al. "Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. "Journal of Medicinal Chemistry 50.10(2007):2341.

영국-371804 준비 용품 및 원자재

원자재

준비 용품

영국-371804 공급 업체

글로벌( 61)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29825	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4822	58
Chengdu Henghui Pharm Tec Co. Ltd.	13540674322 15828370308		CHINA	121	55

영국-371804 관련 검색:

2-cyano-3-(1-phenylindol-3-yl)acrylate