地西拉嗪
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- CAS号:
- 2470-73-7
- 英文名:
- 2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol
- 英文别名:
- Esucos;UCB-3412;Dixyrazine;2-[2-[4-(2-methyl-3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethoxy]ethanol;2-[2-[4-(2-methyl-3-phenothiazin-10-yl-propyl)piperazin-1-yl]ethoxy]ethanol;2-[2-[4-[2-Methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]ethanol;2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol;Ethanol,2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]-
- 中文名:
- 地西拉嗪
- 中文别名:
- 地西拉嗪;化合物 T19286
- CBNumber:
- CB2901901
- 分子式:
- C24H33N3O2S
- 分子量:
- 427.6
- MOL File:
- 2470-73-7.mol
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地西拉嗪化学性质
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熔点:
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192 °C
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沸点:
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590.0±50.0 °C(Predicted)
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密度:
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1.0745 (rough estimate)
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折射率:
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1.6740 (estimate)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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pKa1: 7.8; pKa2: 3.65(at 25℃)
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形态:
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Solid
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颜色:
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White to off-white
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地西拉嗪性质、用途与生产工艺
Dixyrazine 是 Phenothiazine 衍生物，可预防注射硫酸鱼精蛋白引起的脑水肿。
Pretreatment with Dixyrazine 10 mg/kg completely prevents the brain oedema and significantly reduces the albumin increase in cerebrospinal fluid (CSF). The phenothiazine Dixyrazine (5 mg/kg i.v.) has minimal, transient hypotensive effects but significantly reduces the leakage of
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I labelled serum albumin in conscious rats subjected to acute hypertension provoked by i.v. Adrenaline or Bicuculline. The diameters of pial arteries and veins are continuously measured with a multichannel videoangiometer through a closed cranial window in anesthetized rats before and after i.v. injection of Dixyrazine (5 mg/kg). Dixyrazine, 5 mg /kg, induces a slight transitory decrease in blood pressure (10-20 mm Hg). Maximum MAP is slightly but not significantly lower in Dixyrazine-treated rats.
地西拉嗪
上下游产品信息
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-U00153 | 地西拉嗪
Dixyrazine | 2470-73-7 | 1mg | 2400元 |
| 2024/11/08 | HY-U00153 | 地西拉嗪
Dixyrazine | 2470-73-7 | 10 mM * 1 mLin DMSO | 4704元 |
2470-73-7, 地西拉嗪 相关搜索:
- 抑制剂
- C24H33N3O2S
- 化合物 T19286
- 地西拉嗪
- 2470-73-7
- Ethanol,2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]-
- 2-[2-[4-(2-methyl-3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethoxy]ethanol
- 2-[2-[4-(2-methyl-3-phenothiazin-10-yl-propyl)piperazin-1-yl]ethoxy]ethanol
- UCB-3412
- Esucos
- 2-[2-[4-[2-Methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]ethanol
- Dixyrazine
- 2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol