倍氯米松
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- CAS号:
- 2414276-32-5
- 英文名:
- NEP
- 英文别名:
- NEP
- 中文名:
- 倍氯米松
- 中文别名:
- CBNumber:
- CB48648318
- 分子式:
- C29H31AsN4O5S2
- 分子量:
- 654.63
- MOL File:
- 2414276-32-5.mol
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倍氯米松化学性质
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酸度系数(pKa):
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11.42±0.20(Predicted)
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倍氯米松性质、用途与生产工艺
NEP (VDP-green (NEP)) 是一种基于分子内电荷转移 (ICT) 机制的感应荧光探针，用于感应含邻二硫醇的蛋白质 (VDPs)。NEP 在活细胞和动物体内对 VDPs 表现出高选择性，并显示强绿色荧光信号 (λex/λem=430/535 nm)。NEP 具有用于帕金森氏症研究的潜力。
NEP (1-30 μM; 6 hours) has no or little cytotoxicity in HepG2 and PC12 cells.
NEP (10 μM; 4 hours) causes the fluorescence intensity to decrease gradually in PC12 cells pretreated with 6-OHDA (0, 50, 100, and 200 μM; for 30 min).
NEP contains a dithiarsolane moiety (five-membered As-S ring) as the receptor of VDPs. In the presence of VDPs, NEP displays a strong green fluorescence signal produced by the cyclic dithiarsolane cleavage and subsequent intramolecular cyclization to liberate the fluorophore. NEP maintains a reliable fluorescence response within the range of pH 7-10.
NEP (10 μM; for 4 h) causes the obvious green signal in zebrafishes (4 day old).
倍氯米松
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2023/03/20 | HY-D1259 | NEP | | 5 mg | 3500元 |
| 2023/03/20 | HY-D1259 | NEP | | 10 mg | 5800元 |
2414276-32-5, 倍氯米松 相关搜索:
- C29H31AsN4O5S2
- 2414276-32-5
- NEP