拉伏替丁
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- CAS号:
- 76956-02-0
- 英文名:
- Lavoltidine
- 英文别名:
- Loxtidina;loxtidine;AH-234844;Lavoltidine;Lavoltidina;Lavoltidinum;Lavoltidine [inn:ban];Lavoltidinum [inn-latin];Lavoltidina [inn-spanish];86160-82-9 (Hemisuccinate[1:1])
- 中文名:
- 拉伏替丁
- 中文别名:
- 拉伏替丁;化合物 T15722
- CBNumber:
- CB81179004
- 分子式:
- C19H29N5O2
- 分子量:
- 359.471
- MOL File:
- 76956-02-0.mol
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拉伏替丁性质、用途与生产工艺
Lavoltidine (Loxtidine) 是一种具有口服活性的，不可逆且高效的组胺 H2 受体拮抗剂。Lavoltidine 强烈抑制胃酸分泌，并诱发高胃泌素血症。
Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in
H felis
-infected INS-GAS mice.
Lavoltidine treatment for 6 months inhibits gastric tumors in
H felis
-infected INS-GAS mice.
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Animal Model:
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Male hypergastrinemic mice (INS-GAS mice) infected with
Helicobacter felis
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Dosage:
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0.5 g/L
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Administration:
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Orally (drinking water); changed weekly; for 3 months
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Result:
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Showed partial suppression of both gastric acid secretion and progression to neoplasia.
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拉伏替丁
上下游产品信息
上游原料
下游产品
76956-02-0, 拉伏替丁 相关搜索:
- 化合物 T15722
- 拉伏替丁
- 76956-02-0
- AH-234844
- loxtidine
- Lavoltidine
- Loxtidina
- Lavoltidinum [inn-latin]
- Lavoltidinum
- Lavoltidine [inn:ban]
- Lavoltidina [inn-spanish]
- Lavoltidina
- 86160-82-9 (Hemisuccinate[1:1])
- 1H-1,2,4-Triazole-3-methanol, 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)-
- 1-Methyl-5-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]amino]-1H-1,2,4-triazole-3-methanol