拉伏替丁
中文名称 | 拉伏替丁 |
---|---|
中文同义词 | 拉伏替丁;化合物 T15722 |
英文名称 | Lavoltidine |
英文同义词 | 1-Methyl-5-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]amino]-1H-1,2,4-triazole-3-methanol;1H-1,2,4-Triazole-3-methanol, 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)-;86160-82-9 (Hemisuccinate[1:1]);Lavoltidina;Lavoltidina [inn-spanish];Lavoltidine [inn:ban];Lavoltidinum;Lavoltidinum [inn-latin] |
CAS号 | 76956-02-0 |
分子式 | C19H29N5O2 |
分子量 | 359.471 |
EINECS号 | |
相关类别 | |
Mol文件 | 76956-02-0.mol |
结构式 | ![]() |
拉伏替丁 性质
H 2 Receptor
|
Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in
H felis
-infected INS-GAS mice.
Lavoltidine treatment for 6 months inhibits gastric tumors in
H felis
-infected INS-GAS mice.
Animal Model: | Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis |
Dosage: | 0.5 g/L |
Administration: | Orally (drinking water); changed weekly; for 3 months |
Result: | Showed partial suppression of both gastric acid secretion and progression to neoplasia. |