TCPOBOP
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- CAS号:
- 76150-91-9
- 英文名:
- TCPOBOP
- 英文别名:
- TCPOBOP;3,3',5,5'-TETRACHLORIDE-BPB;TCPOBOP - CAS 76150-91-9 - Calbiochem;inhibit,Bcl-2 Family,TCPOBOP,Inhibitor;1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene;1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE;1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene;TCPOBOP, Androstane receptor (mCAR) agonist;3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE;1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene
- 中文名:
- TCPOBOP
- 中文别名:
- 化合物TCPOBOP;1,4-双((3,5-二氯吡啶-2-基)氧基)苯;TCPBOOP,鼠类本构雄激素受体(MCAR)激动剂;TCPOBOP,ANDROSTANE RECEPTOR (MCAR)激动剂
- CBNumber:
- CB8155924
- 分子式:
- C16H8Cl4N2O2
- 分子量:
- 402.06
- MOL File:
- 76150-91-9.mol
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TCPOBOP化学性质
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沸点:
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444.8±45.0 °C(Predicted)
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密度:
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1.518±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO: >10 mg/mL
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形态:
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solid
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酸度系数(pKa):
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-0.52±0.10(Predicted)
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颜色:
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white
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
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TCPOBOP性质、用途与生产工艺
TCPOBOP 是一种组成型雄甾烷受体 (CAR) 激动剂，可诱导强健的肝细胞增殖和肝肿大，无任何肝损伤或组织缺失。TCPOBOP 通过改变 Bcl-2 蛋白减弱 Fas 诱导的小鼠肝损伤。
TCPOBOP (oral; 3 mg/kg; 1-5 days) remarkable increases Liver weight to body weight in LW/BW ratio at 48 hours.
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Animal Model:
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MET
fl/fl
: Tam-Cre
+/+
mice with a targeted deletion for exon 16 with MET KO
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Dosage:
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3 mg/kg
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Administration:
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Oral; 1, 2, 5 days
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Result:
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Increased Liver weight to body weight.
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TCPOBOP
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-103243 | TCPOBOP | | 1 mg | 200元 |
| 2024/11/08 | HY-103243 | TCPOBOP
TCPOBOP | 76150-91-9 | 5mg | 500元 |
76150-91-9, TCPOBOP 相关搜索:
- 抑制剂
- 合成材料中间体
- 合成有机化合物配体
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- Cell Cycle
- Cell Cycle Regulators
- Apoptosis and Cell Cycle
- C16H8Cl4N2O2
- C16H8N2O2Cl4
- TCPOBOP,ANDROSTANE RECEPTOR (MCAR)激动剂
- TCPBOOP,鼠类本构雄激素受体(MCAR)激动剂
- 化合物TCPOBOP
- 1,4-双((3,5-二氯吡啶-2-基)氧基)苯
- 76150-91-9
- TCPOBOP, Androstane receptor (mCAR) agonist
- inhibit,Bcl-2 Family,TCPOBOP,Inhibitor
- Pyridine, 2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro-
- 3,5-dichloro-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}pyridine
- 1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene
- TCPOBOP - CAS 76150-91-9 - Calbiochem
- 3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
- 2,2'-[Benzene-1,4-diylbis(oxy)]bis(3,5-dichloropyridine)
- 2,2'-(p-Phenylenebisoxy)bis(3,5-dichloropyridine)
- 2,2'-(4,1-Phenylenebisoxy)bis(3,5-dichloropyridine)
- 1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene
- 1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene
- 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene, 3,3μ,5,5μ-Tetrachloro-1,4-bis(pyridyloxy)benzene
- 2,2’-(1,4-phenylenebis(oxy))bis(3,5-dichloro-pyridin
- TCPOBOP
- 1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE
- 3,3',5,5'-TETRACHLORIDE-BPB
- 3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE