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TCPOBOP

TCPOBOP Struktur
76150-91-9
CAS-Nr.
76150-91-9
Englisch Name:
TCPOBOP
Synonyma:
TCPOBOP;3,3',5,5'-TETRACHLORIDE-BPB;TCPOBOP - CAS 76150-91-9 - Calbiochem;inhibit,Bcl-2 Family,TCPOBOP,Inhibitor;1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene;1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE;1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene;3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE;1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene;3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
CBNumber:
CB8155924
Summenformel:
C16H8Cl4N2O2
Molgewicht:
402.06
MOL-Datei:
76150-91-9.mol
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TCPOBOP Eigenschaften

Siedepunkt:
444.8±45.0 °C(Predicted)
Dichte
1.518±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
DMSO: >10 mg/mL
Aggregatzustand
solid
pka
-0.52±0.10(Predicted)
Farbe
white
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.

Sicherheit

S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. UT7145000

TCPOBOP Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

TCPOBOP is an agonist for mCAR, inducing cytochrome P450 monooxygenases and multidrug resistance and cenobiotic efflux proteins.

Allgemeine Beschreibung

A highly potent inducer of phenobarbital-like class of cytochrome P450 (CYP) enzymes. A tumor promoter that induces hepatocyte proliferation, independent of the presence of cytokines or transcription factors. Activates orphan nuclear receptors mCAR (mouse constitutive androstane receptor) and hPXR (human pregane X receptor), but has little or no effect on hCAR and mPXR. Also suppresses the expression of multi-drug resistance genes mdr2 and mdr3 in mouse liver.

Biochem/physiol Actions

TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents.

TCPOBOP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

TCPOBOP Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 75)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49739 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14059 65
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826
 market@aladdin-e.com China 25014 65
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60

76150-91-9()Verwandte Suche:

(+)-Brefeldin A 3,5-Dichlorpyridin 3,5-Dichlor-2-pyridon 5-Chlorpyridin-2-ol
  • 3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE
  • 3,3',5,5'-TETRACHLORIDE-BPB
  • 1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE
  • TCPOBOP
  • 2,2’-(1,4-phenylenebis(oxy))bis(3,5-dichloro-pyridin
  • 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene, 3,3μ,5,5μ-Tetrachloro-1,4-bis(pyridyloxy)benzene
  • 1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene
  • 1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene
  • 2,2'-(4,1-Phenylenebisoxy)bis(3,5-dichloropyridine)
  • 2,2'-(p-Phenylenebisoxy)bis(3,5-dichloropyridine)
  • 2,2'-[Benzene-1,4-diylbis(oxy)]bis(3,5-dichloropyridine)
  • 3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
  • TCPOBOP - CAS 76150-91-9 - Calbiochem
  • 1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene
  • 3,5-dichloro-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}pyridine
  • Pyridine, 2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro-
  • inhibit,Bcl-2 Family,TCPOBOP,Inhibitor
  • 76150-91-9
  • C16H8N2O2Cl4
  • C16H8Cl4N2O2
  • Apoptosis and Cell Cycle
  • Cell Cycle Regulators
  • Cell Cycle
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
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