1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine

763111-49-5

CAS-Nr.: 763111-49-5

Englisch Name:: 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine

Synonyma:: KU0058948;KU 0058948;KU-0058948;Venadaparib Impurity 1;1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine;4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]Methyl]-1(2H)-phthalazinone;1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]methyl]-

CBNumber:: CB02622756

Summenformel:: C21H21FN4O2

Molgewicht:: 380.42

MOL-Datei:: 763111-49-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 14

1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Eigenschaften

Schmelzpunkt:: >150°C (dec.)

storage temp.: Refrigerator

Löslichkeit: DMSO (Slightly), Methanol (Slightly)

Aggregatzustand: Solid

Farbe: Pale Yellow to Yellowish Beige

Sicherheit

1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro

1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 14)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Tcichem, Inc.	13918644899	tianchong009@hotmail.com	China	1763	55
Shanghai Benso Pharmaceutical Technology Co., Ltd.	15088289376	248775804@qq.com	China	4972	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	56086	58
Wuxi Donghe Pharmaceutical Technology Co., Ltd.	63313187 15358055255	63313187@qq.com	China	1966	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
guoyungurui	18162595016	3287908757@qq.com	China	10338	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28070	58

1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine
4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]Methyl]-1(2H)-phthalazinone
KU 0058948
KU0058948
KU-0058948
1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]methyl]-
Venadaparib Impurity 1
763111-49-5
Apoptosis
Aromatics
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals