CD38 inhibitor 78c

1700637-55-3

CAS-Nr.: 1700637-55-3

Englisch Name:: CD38 inhibitor 78c

Synonyma:: 78c;cd38-1;MDK7553;MDK 7553;MDK-7553;CD38i_78c;CD38IN-78c;CD38 IN-78c;CD38-IN-78c;Compound-78c

CBNumber:: CB04667733

Summenformel:: C22H27N3O3S

Molgewicht:: 413.53

MOL-Datei:: 1700637-55-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 60

CD38 inhibitor 78c Eigenschaften

Siedepunkt:: 589.8±50.0 °C(Predicted)

Dichte: 1.27±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO : 25 mg/mL (60.46 mM; ultrasonic and warming and heat to 60°C)

Aggregatzustand: A solid

pka: 3.17±0.20(Predicted)

Farbe: Light yellow to brown

InChI: InChI=1S/C22H27N3O3S/c1-25-20-8-3-15(21-13-23-14-29-21)11-18(20)19(12-22(25)26)24-16-4-6-17(7-5-16)28-10-9-27-2/h3,8,11-14,16-17,24H,4-7,9-10H2,1-2H3/t16-,17-

InChIKey: VJQALSOBHVEJQM-QAQDUYKDSA-N

SMILES: N1(C)C2=C(C=C(C3SC=NC=3)C=C2)C(N[C@@H]2CC[C@@H](OCCOC)CC2)=CC1=O

Sicherheit

CD38 inhibitor 78c Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Thiazoloquin(az)olin(on)es, such as the small molecule 78c, have been identified as potent CD38 inhibitors (CD38i). CD38 inhibitor 78c is a potent, reversible, and uncompetitive inhibitor of CD38. 78c reverses age-related NAD+ decline and ameliorates several metabolic, structural, and molecular ageing features in chronologically aged and progeroid mice. The CD38 inhibitor 78c increases naturally aged mice's lifespan and health span. In addition to a 10% increase in median survival, 78c improved exercise performance, endurance, and metabolic function in mice. The effects of 78c were different between the sexes[1-2].

Verwenden

4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-Quinolinone is a useful compound and has been evaluated for use as CD38 inhibitors.

CD38 inhibitor 78c Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CD38 inhibitor 78c Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 60)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Hubei Chuchang Biotech Co., Ltd.	+undefined15623860702	info@chuchangbiotech.com	China	111	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	13186	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58

CD38 inhibitor 78c
CD38 inhibitor 1
2(1H)-Quinolinone, 4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-
CD38 inhibitor 1 (compound 78c)
4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-Quinolinone
4-((trans-4-(2-Methoxyethoxy)cyclohexyl)amino)-1-methyl-6-(thiazol-5-yl)quinolin-2(1H)-one
cd38-1
CD38 inhibitor 1,Inhibitor,inhibit,CD-38 inhibitor 1
4-[[trans-4-(2-Methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)quinolin-2(1H)-one
4- (trans 4- (2-methoxyethoxy) cyclohexyl) amino) -1-methyl-6- (thiazol-5-yl) quinoline-2 (1H) - one
CD38 IN-78c
CD38-IN-78c
CD38IN-78c
Cluster of Differentiation 38 Inhibitor
Compound-78c
MDK 7553
MDK7553
MDK-7553
78c
CD38i_78c
CD38IN-78c: CD38 inhibitor 78c
1700637-55-3