BIBU 1361 DIHYDROCHLORIDE

793726-84-8

CAS-Nr.: 793726-84-8

Englisch Name:: BIBU 1361 DIHYDROCHLORIDE

Synonyma:: BIBU 1361;BIBU1361 (BIBU 1361 );BIBU 1361 DIHYDROCHLORIDE;N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]pyrimido[5,4-d]pyrimidin-4-amine;Pyrimido[5,4-d]pyrimidin-4-amine, N-(3-chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-;N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-aminedihydrochloride;N-(3-CHLORO-4-FLUOROPHENYL)-6-[4-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]-PYRIMIDO[5,4-D]PYRIMIDIN-4-AMINE DIHYDROCHLORIDE

CBNumber:: CB0840882

Summenformel:: C22H27ClFN7

Molgewicht:: 443.95

MOL-Datei:: 793726-84-8.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 20

BIBU 1361 DIHYDROCHLORIDE Eigenschaften

Siedepunkt:: 580.0±60.0 °C(Predicted)

Dichte: 1.285±0.06 g/cm3(Predicted)

storage temp.: Desiccate at +4°C

Löslichkeit: DMSO (Slightly), Methanol (Very Slightly)

Aggregatzustand: Solid

pka: 10.32±0.25(Predicted)

Farbe: Yellow

Sicherheit

BIBU 1361 DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivität

Potent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC 50 = 3 nM). Displays ~ 100-fold lower potency against ErbB2 (IC 50 = 290 nM) and is selective over a range of other related tyrosine kinases (IC 50 > 10 μ M). Blocks downstream EGFR signaling events such as MAPKK/MAPK activation. Oral administration inhibits growth of established human xenografts in athymic mice.

BIBU 1361 DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BIBU 1361 DIHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 20)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
BOC Sciences	--	info@bocsci.com	USA	0	65
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

N-(3-CHLORO-4-FLUOROPHENYL)-6-[4-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]-PYRIMIDO[5,4-D]PYRIMIDIN-4-AMINE DIHYDROCHLORIDE
BIBU 1361 DIHYDROCHLORIDE
N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-aminedihydrochloride
N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]pyrimido[5,4-d]pyrimidin-4-amine
BIBU 1361
BIBU1361 (BIBU 1361 )
Pyrimido[5,4-d]pyrimidin-4-amine, N-(3-chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-
793726-84-8
C22H27ClFN72HCl
C22H27ClFN7